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Cell-based Assay Development

Thu, 01/03/2013 - 1:11pm

CYTOO offers the 2D+ Solutions for cell based assay development in drug discovery. CYTOO’s 2D+ Cell Culture Platform is based on standard and custom adhesive micropatterns in 96-well plates to guide cell architecture and behavior in culture. By defining the 2D topology of cell adhesion, the 2D+ Cell Culture Platform enables fine control of the spreading and 3D shape of cultured cells in single- or multi-cellular configurations. This approach results in control of cell contractility, cell polarity, organelle positioning, and cell division axis. This technology addresses a major concern with traditional 2D culture, in which cells spread and move in an uncontrolled manner, introducing a considerable but unnoticed variability in cell function.

The 2D+ Custom Solutions process includes: Exploratory solutions to guide customers through the initial exploration of the 2D+ technology; Assay development to select the best ecosystem for the requested cells; Screening to run small and medium screens.

CYTOO, 617-674-7711, www.cytoo.com

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