HLA Allele Assay
Tue, 11/27/2007 - 6:13am
MHC-peptide binding assay Class II REVEAL for HLA alleles is a cell-free in vitro assay that can rapidly predict T-cell antigens in any protein sequence. It is widely applicable across many disease areas such as cancer, infectious diseases, autoimmunity and in transplantation, and is suited to therapeutic programs with time pressures, such as the development of vaccines for emerging diseases. Unlike traditional methods for discovering T-cell antigens, such as functional cellular assays, the Class II REVEAL assay does not use patient samples, and determines the HLA restriction of each antigen in a single step.