EMD Millipore, the Life Science division of Merck KGaA, Darmstadt, Germany, and Plasticell of London, UK, announced the availability of OsteoMAX-XF, a fully defined, xeno-free human mesenchymal stem cell differentiation medium for the differentiation of mesenchymal stem cells into osteocytes. Mineralization can be detected in less than one week, whereas competing products that contain serum require approximately 21 days to produce similar levels of bone formation. The formulation, licensed from Plasticell, produces consistent and potent osteogenic differentiation, enabling a reproducible, efficient method for creating bone tissue and advancing research in bone disease and healing. EMD Millipore manufactures and distributes the medium globally for research purposes while Plasticell retains all rights over therapeutic applications. The OsteoMAX-XF differentiation media adds to EMD Millipore’s portfolio of mesenchymal stem cell products including primary human and rat mesenchymal stem cell lines, expansion media, antibodies, characterization kits, growth factors and ECM proteins. The optimized, single application osteogenic medium was developed using Plasticell’s combinatorial screening system that performed a rapid screen of 3,375 combinations of fully defined cell culture media, equivalent to hundreds of thousands of combinations of media components.
EMD Millipore, 800-645-5476, www.millipore.com/stemcell