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Exchanging Out TFA from Synthetic Peptide Preparations: Why it’s Important and How to do it Effectively

November 4, 2015 9:02 am | by Ivona Strug and Timothy Nadler, EMD Millipore Corporation | Articles | Comments

In this case study, we show how Trifluoroacetate (TFA) salts hamper peptide analysis by FTIR spectroscopy. Subsequently, we present a detailed method by which TFA can be exchanged for HCl, with the goal of increasing the reproducibility and accuracy of peptide-based assays.


Early in Breast Cancer, Metastatic Cells are Stem Cell-Like, Offering Targets

November 4, 2015 9:01 am | by Cynthia Fox, Science Writer | Articles | Comments

Early metastatic breast cancer cells are, strikingly, far more like stem cells than other tumor cells, says a new Nature study. They switch from a dormant (and unnoticed) stem cell-like state in primary tumors, to a more active, virulent state when kick-starting regression years later. The discovery could result in earlier detection of—and better drugs for—metastatic breast cancers.


Uninterrupted Sleep May be More Important Than Amount of Sleep

November 4, 2015 9:00 am | by Bevin Fletcher, Associate Editor | News | Comments

Getting uninterrupted sleep may be more important to people’s mood than the overall amount of sleep, according to a new study from Johns Hopkins University.


LED Lights

November 3, 2015 10:12 am | Product Releases | Comments

Terra’s LED strips and panels are low-maintenance and energy-efficient cleanroom-compatible lights that comply with recent energy laws. The bulbs use less energy than traditional incandescent lights and produce less heat than both incandescent and fluorescent bulbs, saving on air cooling costs.

5 Things to Know About Pacific Northwest E.coli Outbreak

November 3, 2015 10:06 am | by Donna Gordon Blankinship, Associated Press | News | Comments

Chipotle has closed 43 of its Pacific Northwest locations in response to an E. coli outbreak health officials have connected to the Mexican food chain. About two dozen people have fallen ill and more were being tested. And at least one lawsuit has already been filed by a woman who says she became sick after eating a burrito bowl at a Vancouver, Washington, Chipotle on Oct. 21. Here are five things to know about the outbreak.


A Protein Atlas of the Brain

November 3, 2015 10:01 am | by Max Planck Institute | News | Comments

To understand the brain’s functions, scientists have for the first time quantified the entire set of proteins ‒ the proteome ‒ in the adult mouse brain. The information about which proteins and how many of them are found in the various cell types and regions has been summarized in a protein atlas.


How Specialized Cells Help Each Other Survive During Stress

November 3, 2015 9:50 am | by The Scripps Research Institute | News | Comments

A team has shown for the first time how one set of specialized cells survives under stress by manipulating the behavior of key immune system cells.


Study Finds Key Molecular Mechanism Regulating Plant Translational Activity

November 3, 2015 9:44 am | by North Carolina State University | News | Comments

Researchers show how plants handle – at the molecular level – the release of ethylene, an important gaseous stress hormone that, among other functions, regulates plant growth and stimulates the fruit ripening process. The findings could pave the way to new techniques to engineer plants to produce better crops or to turn off certain genes.


New Scanner to Help Uncover Causes of Dementia

November 3, 2015 9:38 am | by University of Manchester | News | Comments

The new scanner will help scientists and clinicians understand the causes and progression of dementia, and provide ways to test the effects of new treatments.  Molecular changes in the brain are believed to be responsible for dementia and the scanners have the potential to link these with the brain changes that they cause – leading to new understanding and new treatments.


Study: Deaths Rates Rising in Middle-aged Whites

November 3, 2015 9:29 am | by Mike Stobbe, AP Medical Writer | News | Comments

The U.S. death rate has been falling for decades, but researchers have detected one group in which the rates have been steadily ticking up - middle-aged white people. Suicides and deaths from drug overdose and alcohol abuse are being blamed.


New Computational Strategy Finds Brain Tumor-shrinking Molecules

November 3, 2015 9:16 am | by UC San Diego | News | Comments

Patients with glioblastoma, a type of malignant brain tumor, usually survive fewer than 15 months following diagnosis. Since there are no effective treatments for the deadly disease, researchers developed a new computational strategy to search for molecules that could be developed into glioblastoma drugs. In mouse models of human glioblastoma, one molecule they found shrank the average tumor size by half.


Enhanced Glycoselective Bioaffinity Proteins

November 2, 2015 10:21 am | Product Releases | Comments

AMSBIO has announced the introduction of a range of Recombinant Prokaryotic Lectins (RPLs). RPLs are enhanced glycoselective bioaffinity proteins that enable efficient detection, analysis and selective isolation of glycosylated biomolecules.

Eye’s Recycling Process Key to Seeing Color, Bright Light

November 2, 2015 10:18 am | by Washinton University in St. Louis | News | Comments

Researchers believe they’re now closer to an answer about what keeps cones working and thriving, and that their findings may one day help preserve vision in patients with age-related macular degeneration and other retinal diseases.


More Cases of E. coli in Washington, Oregon Expected

November 2, 2015 10:12 am | by Donna Gordon Blankinship, Associated Press | News | Comments

Health officials expect the number of people sickened by an E. coli outbreak linked to Chipotle restaurants in Washington state and Oregon to grow while they investigate the cause of the infection.


Sweden Projected to Lose 40-80 Days of Snow as Climate Warms

November 2, 2015 10:00 am | by The Associated Press | News | Comments

Snowy white winters are likely to become a thing of the past for most Swedes. The national weather service on Monday released a new analysis of how climate change will affect the Nordic country - and it's bad news for skiing enthusiasts.



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