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Special Report: Many Distant Ancestors of Humans Could Regenerate Limbs, Says New Study

November 10, 2015 8:44 am | by Cynthia Fox, Science Writer | News | Comments

A variety of ancient tetrapods—four-limbed ancestors of man, and modern amphibians, reptiles, and other mammals —could regenerate limbs and tails, says a startling paper in Nature.


Gravity Oven

November 9, 2015 9:54 am | LabStrong Corporation | Product Releases | Comments

LabStrong Corporation, a leader in designing and manufacturing innovative laboratory products, has collaborated with North Central Laboratories (NCL) to create the next generation laboratory gravity oven. The NCL LabStrong Gravity Oven offers significant improvements in performance over existing technology. The oven offers industry leading temperature uniformity performance at an exceptional price point.

Tissue Engineers Recruit Cells to Make Their Own Strong Matrix

November 9, 2015 9:50 am | by Brown University | News | Comments

A team reports culturing cells to make extracellular matrix (ECM) of two types and five different alignments with the strength found in natural tissue and without using any artificial chemicals that could make it incompatible to implant.


Cellular Stress Process Identified in Cardiovascular Disease

November 9, 2015 9:44 am | by Duke University | News | Comments

Combining the investigative tools of genetics, transcriptomics, epigenetics and metabolomics, a research team has identified a new molecular pathway involved in heart attacks and death from heart disease.


Circadian Clock Controls Insulin and Blood Sugar In Pancreas

November 9, 2015 9:39 am | by Northwestern University | News | Comments

A new study has pinpointed thousands of genetic pathways an internal body clock takes to dictate how and when our pancreas must produce insulin and control blood sugar, findings that could eventually lead to new therapies for children and adults with diabetes.


Rocket Scientists Bring Expertise to Analyzing Breath of Sick Children

November 9, 2015 9:28 am | by Stanford University | News | Comments

Three engineering students work to create a disease breathalyzer. It would be a gadget straight out of Star Trek - a quick, noninvasive way to detect everything from diabetes to cancer.


Freshwater Fish, Amphibians Supercharge Their Ability to See Infrared Light

November 9, 2015 9:15 am | by Washington University in St. Louis | News | Comments

Salmon migrating from the open ocean to inland waters do more than swim upstream. To navigate the murkier freshwater streams and reach a spot to spawn, the fish have evolved a means to enhance their ability to see infrared light. Humans lack this evolutionary adaptation.


SfN 2015 Recap: The Role of Synapses, Neural Networks in Alzheimer’s

November 9, 2015 8:49 am | by Stephanie Guzowski, Editor, Drug Discovery & Development | News | Comments

Researchers, for years, have targeted amyloid beta (Aβ) in attempts to halt the progression of Alzheimer’s disease, and have recently, shown increased interest in the protein, tau. But Paula Pousinha, Ph.D., at the French National Centre for Scientific Research, has focused her research on a lesser-known protein fragment: amyloid precursor protein intracellular domain (AICD).


Ventilator for Rodents

November 6, 2015 9:42 am | Product Releases | Comments

Harvard Apparatus is proud to introduce the new VentElite ventilator for rodents.  The VentElite was designed for small animal research applications and is intended for use on subjects ranging in size from mice to guinea pigs. 

Nanoparticle Delivery Maximizes Drug Defense Against Bioterrorism Agent

November 6, 2015 9:38 am | by UCLA | News | Comments

Scientists have developed a nanoparticle delivery system for the antibiotic moxifloxacin that vastly improves the drug’s effectiveness against pneumonic tularemia, a type of pneumonia caused by inhalation of the bacterium Francisella tularensis. The study shows how the nanoparticle system targets the precise cells infected by the bacteria and maximizes the amount of drug delivered to those cells.


Scientists Tinker With Evolution to Save Hawaii Coral Reefs

November 6, 2015 9:25 am | by Caleb Jones, Associated Press | News | Comments

Scientists at a research center on Hawaii's Coconut Island have embarked on an experiment to grow "super coral" that they hope can withstand the hotter and more acidic oceans that are expected with global warming. The quest to grow the hearty coral comes at a time when researchers are warning about the dire health of the world's reefs, which create habitats for marine life, protect shorelines and drive tourist economies.


World First Use of Gene-edited Immune Cells to Treat ‘Incurable’ Leukemia

November 6, 2015 9:07 am | by Great Ormand Street Hospital | News | Comments

A new treatment that uses ‘molecular scissors’ to edit genes and create designer immune cells programmed to hunt out and kill drug resistant leukemia has been used at Great Ormond Street Hospital (GOSH). The treatment, previously only tested in the laboratory, was used in one-year-old, Layla, who had relapsed acute lymphoblastic leukemia (ALL). She is now cancer free and doing well.


Memory Complaints Could Signal Cognitive Impairment Decades Later

November 6, 2015 8:38 am | by Bevin Fletcher, Associate Editor | News | Comments

A new study followed a group of older women for nearly 20 years to assess if subjective memory complaints might signal thinking impairments later. The research, published online Oct. 28 in Neurology, suggests older women who notice memory problems (which are not significant enough to show up on a standard test), may be at higher risk for a diagnosis of cognitive impairment years later.


Immunotherapy: The Need for Immunocompetent Models

November 6, 2015 8:38 am | by Qian Shi, Ph.D., Executive Director of Cancer Pharmacology, Crown Bioscience | Articles | Comments

There is a great unmet need for improved preclinical models, with functional immunity, to drive forward promising immunotherapy research in oncology and to enable the successful transition of immunotherapeutics from the laboratory to the clinic. The benefits these models can provide could drive the development of combination therapy, improving patient comfort and saving lives.



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