It is something of an eternal question: Can we slow or even reverse the aging process? Even though genetic manipulations can, in fact, alter some cellular dynamics, little is known about the mechanisms of the aging process in living organisms. Now scientists from the Florida campus of The Scripps Research Institute have found in animal models that a single gene plays a surprising role in aging that can be detected early on in development.
Researchers have identified a group of cells in the brain that they say plays an important role in the abnormal neuron development in Down syndrome. After developing a new model for studying the syndrome using patient-derived stem cells, the scientists also found that applying an inexpensive antibiotic to the cells appears to correct many abnormalities in the interaction between the cells and developing neurons.
A daily low-dose aspirin is widely prescribed for the prevention of cardiovascular disease. Now, a new study suggests that common genetic variation may modify the cardiovascular benefit of aspirin.
Researchers have uncovered a genetic vulnerability of cancer cells that express telomerase— an enzyme that drives their unchecked growth— and showed that telomerase-expressing cells depend upon a gene named p21 for their survival.
The drugmaker AbbVie has reached a roughly $55 billion deal to combine with British counterpart Shire and become the latest U.S. company to seek an overseas haven from corporate income tax rates back home. The companies said Friday that Shire shareholders will receive cash and stock valued at...
Move over, pot brownies. The proliferation of marijuana edibles for both medical and recreational purposes is giving rise to a cottage industry. Cookbooks, classes and vendors are spreading information on ways to make candies, infused olive oils and more. Many pot users turn to edibles because...
Federal authorities on Thursday charged FedEx with assisting illegal pharmacies by knowingly delivering painkillers and other dangerous drugs to customers without prescriptions. The indictment was filed in federal court in San Francisco, and the Department of Justice announced the charges in...
SAN JUAN, Puerto Rico (AP) — Health officials in Puerto Rico on Thursday declared an epidemic of the mosquito-borne virus known as chikungunya, which was introduced into the Caribbean region late last year. Health Secretary Ana Rius said that more than 200 cases had been confirmed on the island...
AgileBio released a new substructure search engine for its LabCollector Chemical Structures module. Searching molecules can now be easily made using simple SMILES queries or even graphically designed. Queries can also be made by importing MOL representations.
Tecan’s AC Extraction Plate is an automation-friendly solution designed to streamline sample preparation for LC-MS analysis of small molecules. The plate, which is based on proprietary TICE (Tecan Immobilized Coating Extraction) technology, reduces the sample preparation process to a convenient ‘pipette and shake’ routine.
Many promising clinical trials were highlighted at the annual meeting of the International Society of Stem Cell Research (ISSCR). One set of trials highlighted were monogenic gene therapy trials and cancer immunotherapy trials. Also discussed were trials for Parkinson’s disease, Multiple Sclerosis, and potential future trials involving cochlear stem cells.
The common pencil squid (Loliginidae) may hold the key to a new generation of medical technologies that could communicate more directly with the human body. UC Irvine materials science researchers have discovered that reflectin, a protein in the tentacled creature’s skin, can conduct positive electrical charges, or protons, making it a promising material for building biologically inspired devices.
Investigators have identified a gene that underlies a very rare but devastating autoinflammatory condition in children. Several existing drugs have shown therapeutic potential in laboratory studies, and one is currently being studied in children with the disease, which the researchers named STING-associated vasculopathy with onset in infancy (SAVI).
Rice University scientists have succeeded in analyzing transmembrane protein folding in the same way they study the proteins’ free-floating, globular cousins. Rice theoretical biologist Peter Wolynes and his team at the university’s Center for Theoretical Biological Physics (CTBP) have applied his energy landscape theory to proteins that are hard to view because they live and work primarily inside cell membranes.
In mice with diet-induced diabetes, the equivalent of type 2 diabetes in humans, a single injection of the protein FGF1 is enough to restore blood sugar levels to a healthy range for more than two days, according to a new study.