Scientists have now shown how double stranded RNA, such as viral genetic information, is prevented from entering the nucleus of a cell. During the immune response against viral infection, the protein ADAR1 moves from the cell nucleus into the surrounding cytoplasm.
Imaging of the coronary arteries with computed tomography angiography provides an accurate assessment of arterial plaque and could have a dramatic impact on the management of diabetic patients who face a high risk of heart attacks and other cardiovascular events, according to a new study.
A team of researchers has developed a test that can rapidly assess several DNA repair systems, which could help determine individuals’ risk of developing cancer and help doctors predict how a given patient will respond to chemotherapy drugs.
Scientists collaborated on the first large-scale investigation into the evolution of self-control in animals, defined in the study as the ability to inhibit powerful but ultimately counter-productive behavior.
Using reprogrammed skin cells, researchers have for the first time used stem cell techniques to grow fully functional assemblies of the cells that line airways leading to the lungs.
Scientists have worked together to create tools for observing nerves in living animals that signal between themselves in real time, which will help them understand how those individual signals add up to the complex collection of a person's thoughts and memories.
Researchers say that rapid-eye-movement sleep behavior disorder (RBD), which causes people to act out their dreams, is the best current predictor of brain diseases like Parkinson's and Alzheimer's.
Valeant Pharmaceuticals and activist investor Bill Ackman have unveiled details of their offer to buy Botox maker Allergan, proposing a cash-and-stock deal that could be worth about $45 billion. Each Allergan share would be exchanged for $48.30 in cash and 0.83 shares of Valeant Pharmaceuticals...
Swiss pharmaceutical giant Novartis AG announced a series of multibillion-dollar deals Tuesday with other major pharmaceutical companies that it said would reduce sales but boost profitability, while affecting some 15,000 of its employees globally. The Basel, Switzerland-based company said it has...
Saudi Arabia's health ministry says two more patients who contracted a potentially fatal Middle East virus related to SARS have died as the kingdom detected 17 new cases of the disease. The ministry said on Tuesday that a chronically ill 73-year-old Saudi man died in Riyadh. The other victim, a...
Smokers are increasingly turning to battery-powered electronic cigarettes to get their nicotine fix. They're about to find out what federal regulators have to say about the popular devices. The Food and Drug Administration will propose rules for e-cigarettes as early as this month. The rules will...
Muscle weakness from long-term alcoholism may stem from an inability of mitochondria, the powerhouses of cells, to self-repair, according to a new study. In the research, scientists found evidence that chronic heavy alcohol use affects a gene involved in mitochondrial repair and muscle regeneration.
The most effective way to tackle debilitating diseases is to punch them at the start and keep them from growing. Research shows that a small “molecular tweezer” keeps proteins from clumping, the first step of disorders such as Parkinson’s disease, Alzheimer’s disease and Huntington’s disease.
Most drugs used to treat lung, breast and pancreatic cancers also promote drug-resistance and ultimately spur tumor growth. Researchers have discovered a biomarker called CD61 that appears responsible for inducing tumor metastasis by enhancing the stem cell-like properties of cancer cells.
A single type of cell in the lining of the bladder is responsible for most cases of invasive bladder cancer, according to researchers. This study is the first to pinpoint the normal cell type that can give rise to invasive bladder cancers.