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From Mouse Ears to Man's?

March 24, 2014 2:57 pm | News | Comments

One in a thousand children in the United States is deaf, and one in three adults will experience significant hearing loss after the age of 65. Now a team of researchers discovered that using DNA as a drug in laboratory mice may protect the inner ear nerve cells of humans suffering from certain types of progressive hearing loss.

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A Key Link Between Tumors and Healthy Tissue Identified

March 24, 2014 2:49 pm | News | Comments

The delicate balance between development of normal tissue and tumors depends in part upon a key molecular switch within cells, Yale School of Medicine researchers report. Their findings reveal a potential mechanism used by cancer cells to recruit healthy cells to promote tumor growth and suggest new strategies to generate healthy tissue.

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Electronic Lab Notebook

March 24, 2014 2:44 pm | Product Releases | Comments

AgileBio released a new version of its Electronic Lab Notebook (ELN), a complimentary application for its LIMS, LabCollector. ELN is designed to store, organize, find and share all researchers’ laboratory experiments in a variety of life sciences and other industries as well as in academic research laboratories.

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The Aging Brain Needs REST

March 24, 2014 2:39 pm | News | Comments

Why do neurodegenerative diseases such as Alzheimer’s affect only the elderly? More than a century of research into the causes of dementia has focused on the clumps and tangles of abnormal proteins that appear in the brains of people with neurodegenerative diseases. However, scientists know that at least one piece of the puzzle has been missing because some people with these abnormal protein clumps show few or no signs of cognitive decline.

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Cellular 'Counting' of Rhythmic Signals Synchronizes Changes in Cell Fate

March 24, 2014 2:28 pm | News | Comments

Biologists  discovered that when biological signals hit cells in rhythmic waves, the magnitude of the cells' response can depend on the number of signaling cycles—not their strength or duration. Because such so-called “oscillating signaling cycles” are common in many biological systems, the findings in single-celled organisms could help explain the molecular workings of phenomena such as tissue and organ formation.

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Gene Expression Signature Reveals New Way to Classify Gum Disease

March 24, 2014 2:17 pm | News | Comments

Researchers at Columbia University Medical Center have devised a new system for classifying periodontal disease based on the genetic signature of affected tissue, rather than on clinical signs and symptoms. The new classification system may allow for earlier detection and more individualized treatment of severe periodontitis, before loss of teeth and supportive bone occurs.

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Cells Get Ready for Their Close-up

March 24, 2014 2:11 pm | News | Comments

In 2007, MIT scientists developed a type of microscopy that allowed them to detail the interior of a living cell in three dimensions, without adding any fluorescent markers or other labels. This technique also revealed key properties, such as the cells’ density. Now the researchers have adapted that method so they can image cells as they flow through a tiny microfluidic channel.

Engineers Design ‘Living Materials’

March 24, 2014 1:51 pm | News | Comments

Inspired by natural materials such as bone—a matrix of minerals and other substances, including living cells—MIT engineers have coaxed bacterial cells to produce biofilms that can incorporate nonliving materials, such as gold nanoparticles and quantum dots.

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Ebola outbreak in Guinea may spread to Liberia

March 24, 2014 1:19 pm | by Boubacar Diallo - Associated Press - Associated Press | News | Comments

An outbreak of the deadly Ebola virus is believed to have killed at least 59 people in Guinea and may already have spread to neighboring Liberia, health officials said Monday. Health workers in Guinea are trying to contain the spread of the disease which causes severe internal bleeding. In...

FDA reviews DNA-based colon cancer screening kits

March 24, 2014 12:19 pm | by Matthew Perrone - AP Health Writer - Associated Press | News | Comments

The Food and Drug Administration is weighing the benefits and risks of two experimental colon cancer screening tests which use DNA from a patient's stool to detect dangerous tumors and growths. FDA scientists have questions about the accuracy and the potential real-world impact of the kits from...

Study ties breast gene to high-risk uterine cancer

March 24, 2014 11:17 am | by Marilynn Marchione - AP Chief Medical Writer - Associated Press | News | Comments

Women with a faulty breast cancer gene might face a greater chance of rare but deadly uterine tumors despite having their ovaries removed to lower their main cancer risks, doctors are reporting. A study of nearly 300 women with bad BRCA1 genes found four cases of aggressive uterine cancers years...

Nature Rejects Challenge to "Acid Stem Cells"; Scientists Try New Tips

March 24, 2014 9:51 am | by Cynthia Fox | Blogs | Comments

Nature has rejected the paper of a top Hong Kong researcher whose lab several times failed to replicate results of the now-famous “acid bath” stem cell papers. That researcher is now trying to reproduce the work as it appears in yet another new updated protocol, posted Thursday by Harvard researchers. Meanwhile, in interviews, Harvard's Vacanti clarifies some mysteries.

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Bugs resistant to genetically modified corn found

March 23, 2014 8:16 pm | by The Associated Press | News | Comments

Researchers say bugs are developing resistance to the widely popular genetically engineered corn plants that make their own insecticide, so farmers may have to make changes. The Lincoln Journal Star reports ( http://bit.ly/1eC05SM ) that cases of rootworms eating roots of so-called Bt corn have...

FDA approves specialty arthritis drug from Celgene

March 21, 2014 6:16 pm | by The Associated Press | News | Comments

The Food and Drug Administration on Friday said it approved Celgene Corp.'s drug Otezla to treat adults with psoriatic arthritis. Psoriatic arthritis is a form of arthritis that causes joint pain, stiffness and swelling in patients with psoriasis. The FDA said it approved the drug based on three...

Digital PCR System Aids Life Science Experiments

March 21, 2014 2:06 pm | Product Releases | Comments

Bio-Rad Laboratories Inc. launched the QX200 Droplet Digital PCR (ddPCR) system, the second generation of the company's ddPCR technology. The system is the only digital PCR system that works with EvaGreen and TaqMan hydrolysis probes (reagents that are used with the instrument) to provide users more flexibility in the design of their digital PCR experiments.

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