Biologists at UC San Diego have found the “missing link” in the chemical system that enables animal cells to produce ribosomes—the thousands of protein “factories” contained within each cell that manufacture all of the proteins needed to build tissue and sustain life.
The Ebola outbreak ravaging West Africa is "totally out of control," according to a senior official for Doctors Without Borders, who says and the medical group is stretched to the limit in its capacity to respond. International organizations and the governments involved need to send in more...
WHITEHOUSE STATION, N.J. (AP) — Merck is starting a tender offer on Friday to buy all of the outstanding shares of hepatitis C treatment maker Idenix Pharmaceuticals Inc. Merck & Co. announced earlier this month that it would pay about $3.85 billion for the Cambridge, Massachusetts-based...
The Dublin-based drugmaker Shire PLC says it has rejected an unsolicited cash and share offer from AbbVie Inc., arguing that it fundamentally undervalued the company and its prospects. The company said in a statement Friday that U.S.-based AbbVie's proposal was 20.44 pounds ($34.78) and 0.7988...
In a skeleton more than 6,200 years old, scientists have found the earliest known evidence of infection with a parasitic worm that now afflicts more than 200 million people worldwide. Archaeologists discovered a parasite egg near the pelvis of a child skeleton in northern Syria and say it dates back to a time when ancient societies first used irrigation systems to grow crops.
A piece of detective work has mapped a special gene variant among Greenlanders that plays a particularly important role in the development of type 2 diabetes. The results can be used to improve prevention and treatment options for those genetically at-risk.
A new study shows that the brain cells surrounding a mouse’s neurons do much more than fill space. According to the study, the cells can monitor and respond to nearby neural activity, but only after being activated by the fight-or-flight chemical norepinephrine.
It’s a long way from DNA to RNA to protein, and only about two percent of a person’s genome is eventually converted into proteins. In contrast, a much higher percentage of the genome is transcribed into RNA. What these non-protein-coding RNAs do is still relatively unknown. However, given their vast numbers in the human genome, researchers believe that they likely play important roles in normal human development and response to disease.
By scouring the DNA of thousands of patients, researchers have discovered four rare gene mutations that not only lower the levels of triglycerides, a type of fat in the blood, but also significantly reduce a person’s risk of coronary heart disease—dropping it by 40 percent. The mutations all cripple the same gene, called APOC3, suggesting a powerful strategy in developing new drugs against heart disease.
Owlstone launched launched its UltraFAIMS series of products, developed to enhance mass spectrometry (MS) by quickly simplifying complex mass spectra, separating isobaric ions and reducing background. UltraFAIMS is a miniaturized chip-based FAIMS (Field Asymmetric Ion Mobility Spectrometry) platform technology developed by Owlstone. It can be interfaced with mass spectrometers to provide an additional in-source separation stage for isobaric analytes, protein and peptide charge states, large and small proteins, isomers and conformers.
UT Arlington researchers have successfully used a portable brain-mapping device to show limited prefrontal cortex activity among student veterans with Post Traumatic Stress Disorder when they were asked to recall information from simple memorization tasks.
Biologists have long considered cells to function like self-cleaning ovens, chewing up and recycling their own worn out parts as needed. But a new study challenges that basic principle, showing that some nerve cells found in the eye pass off their old energy-producing factories to neighboring support cells to be “eaten.”
The circuitry of the central nervous system is immensely complex and, as a result, sometimes confounding. When scientists conduct research to unravel the inner workings at a cellular level, they are sometimes surprised by what they find.
Researchers, tackling a modern challenge of diabetes research, have identified a gene believed to disrupt the ability of beta cells to produce insulin resulting in type 1 diabetes. The loss of beta cell function may be driven by a defect in Clec16a, a gene responsible for getting rid of old mitochondria, and making room for fresh ones. Healthy mitochondria are crucial to allowing beta cells to produce insulin and control blood sugar levels.
Agilent introduced a new triple quadrupole mass spectrometer that is designed for LC/MS applications requiring the highest sensitivity and robustness. The Agilent 6495 LC/MS Triple Quadrupole system is fully integrated with Agilent’s 1200 series UHPLC systems to deliver turnkey performance.