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Biologists Find ‘Missing Link’ in the Production of Protein Factories in Cells

June 23, 2014 1:40 pm | News | Comments

Biologists at UC San Diego have found the “missing link” in the chemical system that enables animal cells to produce ribosomes—the thousands of protein “factories” contained within each cell that manufacture all of the proteins needed to build tissue and sustain life.

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Doctors Without Borders: Ebola 'out of control'

June 20, 2014 10:16 am | by Sarah Dilorenzo - Associated Press - Associated Press | News | Comments

The Ebola outbreak ravaging West Africa is "totally out of control," according to a senior official for Doctors Without Borders, who says and the medical group is stretched to the limit in its capacity to respond. International organizations and the governments involved need to send in more...

Merck starting tender offer for Idenix

June 20, 2014 9:20 am | by The Associated Press | News | Comments

WHITEHOUSE STATION, N.J. (AP) — Merck is starting a tender offer on Friday to buy all of the outstanding shares of hepatitis C treatment maker Idenix Pharmaceuticals Inc. Merck & Co. announced earlier this month that it would pay about $3.85 billion for the Cambridge, Massachusetts-based...

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Drug maker Shire rejects offer from AbbVie

June 20, 2014 7:20 am | by The Associated Press | News | Comments

The Dublin-based drugmaker Shire PLC says it has rejected an unsolicited cash and share offer from AbbVie Inc., arguing that it fundamentally undervalued the company and its prospects. The company said in a statement Friday that U.S.-based AbbVie's proposal was 20.44 pounds ($34.78) and 0.7988...

Scientists Find 6,200-year-old Parasite Egg

June 19, 2014 8:20 pm | by Maria Cheng - AP Medical Writer - Associated Press | News | Comments

In a skeleton more than 6,200 years old, scientists have found the earliest known evidence of infection with a parasitic worm that now afflicts more than 200 million people worldwide. Archaeologists discovered a parasite egg near the pelvis of a child skeleton in northern Syria and say it dates back to a time when ancient societies first used irrigation systems to grow crops.

Scientists Break the Genetic Code for Diabetes in Greenland

June 19, 2014 3:35 pm | Videos | Comments

A piece of detective work has mapped a special gene variant among Greenlanders that plays a particularly important role in the development of type 2 diabetes. The results can be used to improve prevention and treatment options for those genetically at-risk.

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Fight-or-Flight Chemical Primes Cells to Shift Brain from Subdued to Alert

June 19, 2014 3:17 pm | News | Comments

A new study shows that the brain cells surrounding a mouse’s neurons do much more than fill space. According to the study, the cells can monitor and respond to nearby neural activity, but only after being activated by the fight-or-flight chemical norepinephrine.

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Genomic "Dark Matter" of Embryonic Lungs Controls Proper Development of Airways

June 19, 2014 3:11 pm | News | Comments

It’s a long way from DNA to RNA to protein, and only about two percent of a person’s genome is eventually converted into proteins. In contrast, a much higher percentage of the genome is transcribed into RNA. What these non-protein-coding RNAs do is still relatively unknown. However, given their vast numbers in the human genome, researchers believe that they likely play important roles in normal human development and response to disease.

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Broken Gene Found to Protect Against Heart Disease

June 19, 2014 2:41 pm | News | Comments

By scouring the DNA of thousands of patients, researchers have discovered four rare gene mutations that not only lower the levels of triglycerides, a type of fat in the blood, but also significantly reduce a person’s risk of coronary heart disease—dropping it by 40 percent. The mutations all cripple the same gene, called APOC3, suggesting a powerful strategy in developing new drugs against heart disease.

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Accessory for Mass Spectrometers Provides High-speed Separation by Ion Mobility

June 19, 2014 2:26 pm | Product Releases | Comments

Owlstone launched launched its UltraFAIMS series of products, developed to enhance mass spectrometry (MS) by quickly simplifying complex mass spectra, separating isobaric ions and reducing background. UltraFAIMS is a miniaturized chip-based FAIMS (Field Asymmetric Ion Mobility Spectrometry) platform technology developed by Owlstone. It can be interfaced with mass spectrometers to provide an additional in-source separation stage for isobaric analytes, protein and peptide charge states, large and small proteins, isomers and conformers.

Portable Brain-mapping Device Allows Researchers to 'See' Where Memory Fails

June 19, 2014 2:11 pm | News | Comments

UT Arlington researchers have successfully used a portable brain-mapping device to show limited prefrontal cortex activity among student veterans with Post Traumatic Stress Disorder when they were asked to recall information from simple memorization tasks.

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Neurons Get Their Neighbors to Take Out Their Trash

June 19, 2014 2:04 pm | News | Comments

Biologists have long considered cells to function like self-cleaning ovens, chewing up and recycling their own worn out parts as needed. But a new study challenges that basic principle, showing that some nerve cells found in the eye pass off their old energy-producing factories to neighboring support cells to be “eaten.”

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Exploring How the Nervous System Develops

June 19, 2014 1:49 pm | News | Comments

The circuitry of the central nervous system is immensely complex and, as a result, sometimes confounding. When scientists conduct research to unravel the inner workings at a cellular level, they are sometimes surprised by what they find.

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Genetic Risk for Type 1 Diabetes Driven by Faulty Cell Recycling

June 19, 2014 1:38 pm | News | Comments

Researchers, tackling a modern challenge of diabetes research, have identified a gene believed to disrupt the ability of beta cells to produce insulin resulting in type 1 diabetes. The loss of beta cell function may be driven by a defect in Clec16a, a gene responsible for getting rid of old mitochondria, and making room for fresh ones. Healthy mitochondria are crucial to allowing beta cells to produce insulin and control blood sugar levels.

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LC/MS Triple Quadrupole Mass Spectrometer

June 19, 2014 11:12 am | Product Releases | Comments

Agilent introduced a new triple quadrupole mass spectrometer that is designed for LC/MS applications requiring the highest sensitivity and robustness. The Agilent 6495 LC/MS Triple Quadrupole system is fully integrated with Agilent’s 1200 series UHPLC systems to deliver turnkey performance.

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