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Gene Sequencing Project Discovers Common Driver of a Childhood Brain Tumor

February 20, 2014 1:28 pm | News | Comments

The St. Jude Children’s Research Hospital-Washington University Pediatric Cancer Genome Project has identified the most common genetic alteration ever reported in the brain tumor ependymoma and evidence that the alteration drives tumor development. The results provide a foundation for new research to improve diagnosis and treatment of ependymoma, the third most common brain tumor in children.

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Team Discovers Genetic Disorder Causing Strokes and Vascular Inflammation in Children

February 20, 2014 1:22 pm | News | Comments

National Institutes of Health researchers have identified gene variants that cause a rare syndrome of sporadic fevers, skin rashes and recurring strokes, beginning early in childhood. The team’s discovery coincides with findings by an Israeli research group that identified an overlapping set of variants of the same gene in patients with a similar type of blood vessel inflammation.

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Iron Deficiency May Increase Stroke Risk Through Sticky Blood

February 20, 2014 1:15 pm | News | Comments

Scientists discovered that iron deficiency may increase stroke risk by making the blood more sticky. The findings could ultimately help with stroke prevention. The team found that iron deficiency increases the stickiness of platelets, which initiate blood clotting when they stick together. Although a link between iron deficiency and sticky platelets was first discovered almost 40 years ago, its role has been overlooked until now.

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Cell Behavior in Low Oxygen Conditions Mapped

February 20, 2014 12:09 pm | News | Comments

Research at the University of Liverpool has explained how cells behave when placed in a low oxygen environment, a development that could have implications for cancer patients and other serious illnesses. The research opens up the possibility of controlling the signals that keep cells alive, preventing the damages caused by ischemia—a restriction of blood supply to tissues. It could also work to help destroy cancer cells.

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An Essential Step Toward Printing Living Tissues

February 20, 2014 11:55 am | Videos | Comments

A new bioprinting method creates intricately patterned 3D tissue constructs with multiple types of cells and tiny blood vessels. The work represents a major step toward a longstanding goal of tissue engineers: creating human tissue constructs realistic enough to test drug safety and effectiveness.

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Bevacizumab offers no benefit for newly diagnosed glioblastoma

February 20, 2014 10:20 am | by MD Anderson Cancer Center | News | Comments

The angiogenesis inhibitor bevacizumab (Avastin) failed to increase overall survival (OS) or statistically significant progression-free survival (PFS) for glioblastoma patients in the frontline setting, according to a study led by researchers at The University of Texas MD Anderson Cancer Center.

GRU Cancer Center partners with Advaxis to conduct four clinical trials

February 19, 2014 5:11 pm | by Georgia Regents University | News | Comments

Advaxis Inc., a biotechnology company specializing in cancer immunotherapies, announced it has expanded its relationship with the GRU Cancer Center by entering into a master clinical trial agreement. Under the terms of the agreement, the Cancer Center will conduct four Phase 1/2 clinical trials under the supervision of Cancer Center Director Dr. Samir N. Khleif. The planned trials will further develop Advaxis’ two lead immunotherapies: ADXS-HPV for cervical cancer and ADXS-cHER2 for breast cancer. “The preclinical success we have had with the Advaxis platform technology has prompted...

Guidelines to reduce C-section births urge waiting

February 19, 2014 5:08 pm | by Lauran Neergaard - AP Medical Writer - Associated Press | News | Comments

Show more patience in the delivery room: That's the prescription being given to the nation's obstetricians. New guidelines say doctors should give otherwise healthy women more time to deliver their babies vaginally before assuming that labor has stalled. The recommendations are the latest in...

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Jazz Study Shows Link Between Music and Language

February 19, 2014 5:08 pm | by Lauran Neergaard - AP Medical Writer - Associated Press | News | Comments

Jazz musicians are famous for their musical conversations — one improvises a few bars and another plays an answer. Now research shows some of the brain's language regions enable that musical back-and-forth much like a spoken conversation. It gives new meaning to the idea of music as a universal language.

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Technique Could Lead to New Treatments for Pain

February 19, 2014 2:10 pm | News | Comments

The mice in Scott Delp's lab, unlike their human counterparts, can get pain relief from the glow of a yellow light. Right now these mice are helping scientists to study pain—how and why it occurs and why some people feel it so intensely without any obvious injury. But Delp, a professor of bioengineering and mechanical engineering, hopes one day the work he does with these mice could also help people who are in chronic, debilitating pain.

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Researchers Develop Sticky Nanoparticles to Fight Heart Disease

February 19, 2014 2:05 pm | Videos | Comments

Clemson University researchers have developed nanoparticles that can deliver drugs targeting damaged arteries, a non-invasive method to fight heart disease. One of the standard ways to treat clogged and damaged arteries currently is to implant vascular stents, which hold the vessels open and release such drugs as paclitaxel. The researchers hope their advanced nanoparticles could be used alongside stents or in lieu of them.

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Binge Drinking Impairs Bone Healing

February 19, 2014 1:54 pm | by Cynthia Fox | Articles | Comments

Binge drinking impairs the healing of broken bones. It can do this weeks after a binge. And it can leave in its wake permanently inferior bone, according to recent studies. One reason: alcohol slows down mesenchymal (bone, fat, and cartilage) stem cells (MSCs), in the bloodstream, trying to home to fracture sites. And when MSCs finally reach fracture sites, alcohol keeps them from properly replacing lost cells.

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Artificial Leaf Jumps Developmental Hurdle

February 19, 2014 1:41 pm | News | Comments

ASU scientists, along with colleagues at Argonne National Laboratory, have reported advances toward perfecting a functional artificial leaf. Designing an artificial leaf that uses solar energy to convert water cheaply and efficiently into hydrogen and oxygen is one of the goals of BISfuel—the Energy Frontier Research Center.

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IOC Considers Independent Body for Whistleblowers

February 19, 2014 1:36 pm | by STEPHEN WILSON, AP Sports Writer | News | Comments

The IOC will consider setting up an independent body that allows whistleblowers to report information on doping, match-fixing and sexual abuse without fear of reprisals. Swiss member Denis Oswald made the proposal during a debate on "protecting clean athletes."

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Incubator Has Variable Oxygen Control

February 19, 2014 1:23 pm | Thermo Fisher Scientific | Product Releases | Comments

The Thermo Scientific Heracell i CO2 incubator features variable oxygen control. Ideal for advanced applications in the area of stem cell research, regenerative and personalized medicine and other protocols that necessitate reduced oxygen concentrations, the incubator models are also available for hypoxic experimentation where oxygen levels above atmospheric levels are required.

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