Pall Corporation offers the XRS 20 Bioreactor System, a bioreactor with unique agitation properties that incorporates a single-use, easy-to-use Allegro 3-D biocontainer. This next generation “rocker” bioreactor is designed for cultivation of mammalian cells in suspension culture.
Accumulation of DNA damage can cause aggressive forms of cancer and accelerated aging, so the body’s DNA repair mechanisms are normally key to good health. However, in some diseases the DNA repair machinery can become harmful. Now, scientists have discovered some of the key proteins involved in one type of DNA repair gone awry.
Researchers have discovered how a gene commonly linked to obesity—FTO—contributes to weight gain. The study shows that variations in FTO indirectly affect the function of the primary cilium, a little-understood hair-like appendage on brain and other cells.
A new study revealed how T cells, the immune system's foot soldiers, respond to an enormous number of potential health threats and found surprising similarities in the way immune system defenders bind to disease-causing invaders.
In a discovery at the Children’s Medical Center Research Institute at UT Southwestern (CRI), a research team has taken a significant step in cracking the code of an atypical metabolic pathway that allows certain cancerous tumors to thrive, providing a possible roadmap for defeating such cancers.
Working with mice, researchers report they have identified chemical signals that certain breast cancers use to recruit two types of normal cells needed for the cancers’ spread.
Oxford University neuroscientists have shown that fruit flies take longer to make more difficult decisions. In experiments asking fruit flies to distinguish between ever closer concentrations of an odor, the researchers found that the flies don’t act instinctively or impulsively. Instead they appear to accumulate information before committing to a choice.
A new theory about disorders that attack the brain and spinal column has received a significant boost from scientists. The theory attributes these disorders to proteins that act like prions, which are copies of a normal protein that have been corrupted in ways that cause diseases.
Australia can no longer lay claim to the origins of the iconic New Zealand kiwi following University of Adelaide research showing the kiwi's closest relative is not the emu as was previously thought. Instead, the diminutive kiwi is most closely related to the extinct Madagascan elephant bird.
A newly developed fuel-cell concept will allow biodiesel plants to eliminate the creation of hazardous wastes while removing their dependence on fossil fuel from their production process.
Researchers have found a new target for treating chronic pain: an enzyme called PIP5K1C. The research shows that PIP5K1C controls the activity of cellular receptors that signal pain.
Scientists have discovered a pair of genes that normally keeps eating schedules in sync with daily sleep rhythms, and, when mutated, may play a role in so-called night eating syndrome.
In surprise findings, scientists have discovered that a protein with a propensity to form harmful aggregates in the body when produced in the liver protects against Alzheimer’s disease aggregates when it is produced in the brain.
3-D printing promises to revolutionize engineering, and many speculate that it could have a huge impact on medicine, too. Many speculate that useful organs grown in the lab three-dimensionally on scaffolds is now closer to fact than fiction.
Cellexus manufactures the CellMaker, a single-use, disposable, airlift bioreactor system. The Cellexus technology applies airlift methodology designed to simplify cell culture and fermentation in bioresearch, scale-up, production and manufacturing.