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Manufacturing a More Powerful T Cell Against Cancer 4/22/04

April 23, 2004 8:24 am | Articles | Comments

by Elizabeth Tolchin As part of a phase I Small Business Innovation Research (SBIR) grant from the National Cancer Institute, Bethesda, Md., Aastrom Biosciences Inc. will conduct a $124,000, eight-month study to demonstrate the feasibility and advantages of their technology to culture T lymphocytes or T cells for treatment against malignant melanoma.

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Oligos Block Small RNA Function and Call Out Proteins 4/21/04

April 22, 2004 8:11 am | Articles | Comments

by Elizabeth Tolchin Inserting a 2´-O-methyl oligonucleotide into a cell can inhibit small RNA function. That was the method demonstrated by researchers from the University of Massachusetts Medical School, Worcester.

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Mapping Brain Genes in 3D 4/20/04

April 20, 2004 1:02 pm | Articles | Comments

by Elizabeth Tolchin Researchers at the University of Illinois, Chicago, are developing an interactive gene expression map of the brain, as part of The Human Brain Project (HBP).

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Fishing for Antigens in Insects 4/16/04

April 16, 2004 12:39 pm | Articles | Comments

by Elizabeth Tolchin A baculovirus-based method permits insect cells infected with a virus encoding a library of peptides to display unique major histocompatibility complexes (MHCs) on their surface.

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Quantitative Mouse Models Allow Increase or Decrease in Gene Expression 4/15/04

April 15, 2004 11:37 am | Articles | Comments

by Elizabeth Tolchin A pioneer in developing procedures for creating mouse models for gene targeting has now developed a technique for altering the level of expression of a chosen gene in mice without changing its function.

Mississippi Takes on Tobacco-based High-Volume Antibody Expression 4/14/04

April 14, 2004 10:57 am | Articles | Comments

by Robert Ford A five-year agreement between Mississippi State University (MSU), Starkville, Miss., and Toxin Alert Inc., Toronto, Canada, plans to provide research funding to the university for the development of large-scale antibody production in tobacco plants.

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Microplate Reader (3007)

April 14, 2004 10:52 am | Articles | Comments

Model DV990 Microplate Reader is available with or without UV reading capability. In the visible part of the spectra it covers 400-800 nm range. The unit can be equipped with 4-6 filters. Single, double and trichromatic wavelength measurements can be performed.

Ion Exchange Plasmid Purification

April 14, 2004 10:51 am | Articles | Comments

PhoenIX™ Ion Exchange Plasmid Purification System utilizes a solid-phase column with patented resin to both optimize purification and enhance the degree of separation between different biomolecules.

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Life Science/Drug Discovery Research Product Guide

April 14, 2004 10:51 am | Articles | Comments

The Life Science and Drug Discovery Research Product Guide features optimized 96-well filter plates for membrane-based bioassays and bioseparations.

Laboratory Furniture

April 14, 2004 10:51 am | Articles | Comments

Full-color, 272-page Furniture Catalog presents a complete line of metal and wood casework, countertops, fixtures, sinks, tables, seating, fume hoods, workstations, appliances, pre-fabricated rooms, shelving, carts, safety items, and accessories for new and renovated laboratory facilities.

Nucleic Acid Delivery And Labeling Reagents

April 14, 2004 10:51 am | Articles | Comments

Mirus Corp. 2003/2004 catalog provides product data and technical information on nucleic acid delivery and labeling reagents. Discover Trans IT® Transfection Reagents are optimized for specific cell lines and applications such as plasmid and siRNA delivery.

Analysis Of Fibril Elongation By Surface Plasmon Resonance

April 14, 2004 10:32 am | Articles | Comments

Peptide aggregates are associated with several diseases, including Alzheimer's and Huntington's Disease. Surface plasmon resonance (SPR) -amyloid peptide (Ab) (1-40) was monitored

More Than a Quarter of Drug Development Costs Spent on Patient Recruitment 4/13/04

April 13, 2004 1:31 pm | Articles | Comments

by Robert Ford Pharmaceutical companies are finding it more difficult to attract patients to take part in clinical studies, which results in a delay in getting drugs into the marketplace.

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Solid Metal Step Tube Holder

April 12, 2004 7:48 am | Articles | Comments

Solid aluminum step tube holder can hold 64 tubes of 1.5-/2-ml capacity. Step design makes it easy to store, identify, and access sample tubes. Solid metal construction allows samples to be organized in an ice bucket or on a hot plate.

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Cell-Specific Transfection Kits

April 12, 2004 7:48 am | Articles | Comments

ImmunoPoration™ provides high transfection efficiencies in mammalian cells without killing affect, or toxicity or biological problems. A generic kit is available to transfect most cells, and antibody specific kits directly select transfection to the chosen cell type in a heterogeneous sample.

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