American Type Culture Collection offers products for the detection of apoptosis, in tissue samples as well as cells in culture, using methodologies including fluorescence microscopy, flow cytometry, multiwell plate fluorometry, gel electrophoresis, immunochemistry, and radiometric analysis.
The Olympus FluoView FV1000 confocal microscope features a SIM Scanner, which incorporates two independent, fully synchronized laser scanners in a compact design for simultaneous laser stimulation and confocal observation.
Hyaluronic Acid ELISA kit measures HA levels in human or animal biological fluids (blood, serum, urine, diffusate, synovial fluid) or cell supernatants in vitro. Serum HA levels are elevated in several disease states including hepatitis and cirrhosis.
by Elizabeth Tolchin Researchers interested in filamentous fungi will have a new model to derive genetic information from. As part of a five-year, $9 million grant from the National Institutes of Health, researchers from seven universities will collaborate on projects aimed at elucidating the Neurospora crassa (bread mold) genome.
by Elizabeth Tolchin By the end of this year, Eli Lilly & Co. will have five clinical candidates for treatment of obesity entering phase I trials.
by Elizabeth Tolchin Rearchers from PTC Therapeutics identified an enzyme complex that plays a part in the production of transfer ribonucleic acid (tRNA) and RNA processing. The complex also shows a link between the pathways involved in regulating messenger RNA (mRNA).
INTEGRA Biosciences (www.integra-biosciences.com) has announced a new applications study, undertaken in conjunction with Eugenix Biotechnologies (Tagerwilen, Switzerland), describing a disposable flask bioreactor for long-term cultivation of high levels of recombinant proteins.
ProteoSpin™ protein purification product (MDS Sciex) are based on a technology utilizing processed silicon carbide (SiC) as chromatographic matrix. The product line includes three micro kits for processing samples up to 50 g of protein.
Vivascience has announced a new method for sample fractionation prior to 2D - PAGE. The sample fractionation protocol is based on Vivapure centrifugal ion exchange columns. Vivapure anionic ion exchanger (Q) was used to fractionate lysate proteins based on differences in charge.
BD TALON Single Step Columns provide one-step purification of histidine-tagged proteins directly from bacterial culture. Dry-down technology packages dehydrated lysis buffer and resin in a disposable column.
BSI Proteomics is able to provide high resolution images of the drug binding site of protein kinases, which provides a more accurate model for rational drug design. Dynamic Crystallization technologies provide structures of kinases.
ProteomeLab IgG Purity/Heterogeneity Assay is offered in a kit format with a validated standard operating protocol (SOP). It includes all the necessary chemistry components to resolve both native and reduced immunoglobulins by size and to quantify the heterogeneity and impurities present.
Agilent 1100 Series liquid chromatography (LC) micro collection/spotting system, a complete software-controlled product, features direct spotting on matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) targets.
Tripos has released ChemCoreRIO, ChemCoreREG and the Tripos Electronic Notebook, the key components in their informatics product for lab workflows, and SARNavigator and LITHIUM, data analysis and decision support components in their knowledge management solution.
SampleManager 2004 LIMS from Thermo Electron Corp. offers powerful Web capabilities such as XML (eXtensible Markup Language) processing and a Web interface for dynamic data submission. The product is offered for consistent performance and predictable deployments across the global enterprise.