RNAstable directly preserves and stabilizes purified RNA samples at room temperature for at least six months and has demonstrated an equivalent of three and a half years stability under accelerated aging conditions. The product was developed based on the natural principles of anhydrobiosis (life without water), a biological mechanism employed by some multi-cellular organisms that enables their survival while dry for up to 120 years. Anhydrobiotic organisms such as tardigrades and brine shrimp can protect their DNA, RNA, proteins, membranes, and cellular systems for survival and can be revived by simple re-hydration. The molecular principles of anhydrobiosis are transferred to a synthetic chemistry-based stabilization technology. RNAstable works by forming a thermo-stable barrier, essentially "shrink-wrapping" and stabilizing the fragile RNA molecule at ambient temperature and providing protection against degradation.
