The Pico Plus Pump has two syringes and offers flow rates from 1.3 picoliters/min to 1.0 milliliters/min. An RS 232 port provides computer control, and a foot pedal is included with which a user may start or stop the pump. The family of infusion pumps can provide the smooth and accurate flow needed for post-column derivatizations. These pumps provide up to 8,000 psi of pressure with flow rates from 1.3 picoliters/min to greater than 200 milliliters/min.