The 96 channel Platemaker provides both high-throughput liquid transfers and reagent additions on one integrated platform. Maximum throughput is offered for HTS and genomic applications. Independent 96-tip and 8-tip heads can access plates of varying heights in five robot-accessible plate positions. Transfer 500 nanoliters from four 96-well plates to a 384-well plate in less than 4 minutes. The Platemaker is suited to compound reformatting, high throughput PCR, and DNA normalization. Dispense reagents of widely varying viscosity across a broad volume range with precision and accuracy. Nanobuilder software enables a range of applications and data manipulation. Solenoid dispense actuators are isolated from the sample path, and thus never encounter anything other than de-ionized water.