Single-band fluorescence filter sets are optimized for popular quantum dot nanocrystals. Three of these sets are offered for multi-color imaging or quantitation with the highly utilized Qdot 525, 605, and 6Nanocrystals. A fourth filter set uses a long-pass emission filter to allow simultaneous viewing of multi-labeled samples by eye or with a color camera, thus taking advantage of the common blue excitation and narrow, specific visible espectral properties of Qdot nanocrystals. Qdot fluorescence labeling products exhibit excellent imaging performance that comes from robust nanocrystal structure combined with a customizable surface for a wide range of biological applications.