WellAware Pipetting Aid, an error free pipetting system, is a software driven system that can be used for microplate transpositions, serial dilutions, reformatting microplates, cherry-picking, and almost any other custom protocol that requires pipetting. WellAware guides the user by lighting source and target reservoirs on an LCD monitor while supplying text-to-speech audio cues. It can accommodate 1 to 16 channel pipetting between microplates, microtubes, or almost any other liquid reservoir. Individual steps are time-stamped to provide traceability, and a scanner can be used to input data from barcoded labels. A footswitch is available for hands-free operation. The system includes: a computer and monitor, a chemical resistant PET screen cover, a barcode scanner, a footswitch, and software.