U.S. Genomics, Inc.
6H Gill St.
Woburn, MA, 01801
Website: http://www.usgenomics.com
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Benchtop Instrument Detects Individual miRNA Molecules Without Amplification
Trilogy 2020 Single Molecule Analyzer (U.S. Genomics), a benchtop instrumentation, reagents and software platform, directly detects and quantitates individual molecules without amplification. Microfluidics, optical engineering, and labeling strategies combine to eliminate the bias of amplification. As a result, researchers can now accurately examine how cellular elements function and interact within biological pathways. The initial application of the instrument (with the company’s Direct miRNA assays) is the direct detection of microRNA (miRNA) molecules. This molecular group plays a critical role in cell development and has been recently linked to cancer and other major diseases. Known to be difficult and often impossible to amplify, miRNAs regulate the level and activity of other RNAs in the cell. The analyzer accommodates 96- and 384-well plates and can process up to 2000 samples per day. The system is compatible with a range of liquid handling robots. Software streamlines plate and protocol set-up and offers flexible data analysis.
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