Microarray And Software For Comparative Genomic Hybridization Studies In Cancer Research

Agilent Technologies, Inc.

Life Sciences & Chemical Analysis
P.O. Box 51000
Santa Clara, CA, 92055-1000
Website: http://www.agilent.com/chem

Microarray And Software For Comparative Genomic Hybridization Studies In Cancer Research

Human Genome CGH Microarray and CGH Analytics software (Agilent Technologies, Inc.) aids cancer biologists and cytogeneticists in the study of genomic alterations in cancer. Comparative genomic hybridization (CGH) is used to study the chromosomal changes that frequently occur in cancer cells, including the loss or duplication of regions of chromosomal DNA. This microarray-based CGH product enables rapid exploration of chromosomal changes on the same platform used to study gene expression changes. The Agilent Human Genome CGH Microarray provides genome-wide coverage with an emphasis on the most commonly studied genomic coding regions and cancer-related genes.

CGH Analytics software provides a visual environment for exploring array-CGH data. Based on technology developed in Agilent Labs, it uses information visualization theory to leverage visual perception as a means to find interesting patterns in data. The software provides simultaneous visualization of multiple CGH microarray profiles; user-selectable calibration for comparison of profiles; statistical measures to detect aberrant regions; simultaneous chromosome plotting at multiple zoom levels; preloaded gene annotation information from the most recent genome builds; and more.