The Dyversity 2D gel imaging system can be used to assist in identification of proteins associated with directing embryonic stem cells (ESCs) to a particular cell lineage. Scientists in the Institute of Biomedical Engineering at Imperial College are using it to rapidly image 2D DIGE (Differential Gel Electrophoresis) gels containing Cy dye labeled proteins. The proteins were isolated from two different conditioned media, where both media direct murine ESCs to differentiate into mesoderm lineages. Therefore, by identifying and analyzing any common proteins seen on the Dyversity images, researchers at the Institute of Biomedical Engineering in collaboration with the stem cell bio-processing group in the Department of Chemical Engineering, hope to determine which signaling factors direct differentiation.