Krypton Protein Stain fluorescent technology provides sensitivity while minimizing protein quantitation problems associated with differential protein staining. Designed to detect proteins in SDS-PAGE and 2-D gels, Krypton Stain detects down to 2 ng protein in 30 minutes using the rapid protocol. Using the basic (~ 3 hour) protocol, Krypton Stain detects >= 0.25 ng protein. The stain provides high signal intensity with a linear quantitative range of three to four orders of magnitude for a broad range of protein types, which maximizes the detection of low-abundant proteins.