The iTC200 Isothermal Titration Calorimeter determines all binding parameters without the need for immobilization using as little as 5 to 10 µg of protein. Requiring no assay development, the unit addresses the needs of drug discovery and development in such applications as hit selection, lead optimization and binding characterization. It is controlled by an intelligent user interface that assists in experimental design and processes data at the end of sample runs. Results are presented in an Excel format for further analysis or data transfer. For researchers currently working with the VP-ITC, this instrument provides the same data quality two to four times faster using seven-fold less sample volume and up to seven-fold less sample material. For those requiring higher throughput, the iTC200 can be upgraded to the fully automated Auto-iTC200, which is capable of running up to 50 samples a day and 384 samples unattended.
