The PARADIGM Detection Platform is a modular system that can be quickly and easily configured. A selection of cartridges can be interchanged in less than five minutes to meet different assay needs, making the multimode reader useful in labs with multiple users and applications. The high-throughput detector reads on the fly, in formats from six to 1,536 wells. Eight different cartridges are available, based on detection modes including fluorescence polarization, time-resolved fluorescence, dual-label fluorescence (including FRET) and luminescence.