Beckman Coulter, Inc. has added IgY-R7 Rodent and Single-Component Chemistries to its family of ProteomeLab Partitioning Systems, for the isolation and analysis of protein-based biomarkers. The new IgY-R7 Rodent Chemistry selectively partitions seven highly abundant proteins — up to 70 percent of the protein mass — from rat or mouse serum or plasma. The Single-Component kits specifically capture a choice of seven key highly abundant plasma proteins, enabling a targeted approach for protein partitioning. Beckman Coulter's IgY chemistries are based on avian-generated antibodies and offer clean capture and broad antigen-binding host range because of the evolutionary distance between chickens and mammals. The partitioning method enables the investigator to isolate and characterize low and highly abundant proteins. These chemistries produce an enriched proteome plentiful in low-abundant proteins — the primary target for biomarker discovery. The seven proteins captured are albumin, IgG, fibrinogen, transferrin, alpha-1-antitrypsin, haptoglobin and IgM.

Beckman Coulter, Inc.
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