Beckman Coulter, Inc.
Biomedical Research
4300 N. Harbor Blvd.
Fullerton, CA, 92834
Website: http://www.beckman.com
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ADMETox Workstation
The Biomek FX ADMETox Workstation, for in vitro drug permeability measurements, is a validated system that automates the PAMPA (Parallel Artificial Membrane Permeability Analysis) method for the determination of passive absorption of a drug candidate through an artificial lipid membrane. Made possible through a recently announced agreement between Beckman Coulter and pION, Inc., the high-throughput system automates pION’s method for PAMPA analysis on Beckman Coulter’s Biomek FX liquid handling system. With PAMPA, the set up and assay run time enable data collection in less than five hours. The PAMPA method mimics the permeability of drug candidates across the intestinal wall in the human gastrointestinal tract. In addition, the PAMPA method can be run on the Biomek FX ADMETox Workstation to mimic the permeability of drug candidates across the human blood brain barrier. PAMPA Evolution 96 software controls all aspects of the permeability assay including all liquid handling steps.
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