The methylSEQr Bisulfite Conversion Kit is a set of prepackaged reagents for rapid bisulfite conversion, and Methyl Primer Express Software is a free tool that automates the design of methylation-specific PCR or bisulfite sequencing primers. Together the products simplify applications such as bisulfite sequencing and fragment analysis in DNA methylation experiments. The software’s intuitive interface allows researchers to enter their target DNA sequence and simulate bisulfite conversion for methylated and unmethylated genomic DNA.