The IMAP Time Resolved Fluorescence Resonance Energy Transfer (TR-FRET) homogeneous detection system, offered by Molecular Devices for IMAP assay platform, expands the versatility of IMAP by offering both Fluorescence Polarization (FP) and TR-FRET detection, allowing users to select between two well-known detection methods without changing technologies. The system is antibody independent and stable for more than 24 hours. Greater substrate choice enables researchers to work with substrates such as proteins. Sensitivity reduces the amount of enzyme required and lowers assay costs. For screening kinase activity, the assay is applicable to all regions of the human kinome. Assays can be developed for uncommon and proprietary enzymes with a homogeneous, antibody independent system. Using platform binding systems, Substrate Finder Plates, validated substrates, and the FP and TR-FRET detection modes, transitions from assay development, screening and hit evaluation can be accelerated for virtually any kinase with precision and reproducibility.

Molecular Devices Corp.
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