This system incorporates heating and refrigeration modules that maintain a stable temperature between 㪱 and 120 F inside a fully integrated glove box, pass-through or desiccator chamber. The complete system consists of a compressor/condenser and a heater housed inside 304 stainless steel and an evaporator cooler with an integral fan mounted inside the chamber. The closed-loop refrigeration unit operates with CFC-free coolant and uses an RTD sensor with an internal bypass to prevent temperature overshoot. The sensor provides continuous temperature display and a standard controller allows the user to establish a constant temperature set point. PLC-based recipes are available for multiple temperature cycles.