The Cultrex 96-Well BME cell invasion assay offers a flexible, standardized, high-throughput format for quantifying the degree to which invasive cells penetrate a barrier consisting of basement membrane components in vitro in response to chemoattractants and inhibiting compounds. Four formats are offered so cell invasion may be evaluated against different extra-cellular matrices. These matrices include Basement Membrane Extract (BME), Laminin I, Collagen I and Collagen IV.