Covance Research Products
P.O. Box 7200
Denver, PA, 17517
Website: http://www.crpinc.com
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Alzheimer’s Disease Research Tools
The quest for the causative agent in Alzheimer’s Disease has recently focused on the precursors of amyloid plaques. These precursors are part of a bewildering array of processed APP variants, Tau isoforms and secretase components that play a role in neuronal cytotoxicity and subsequent brain dysfunction. A trio of highly-sensitive antibodies to beta-amyloid are available. The affinity-purified rabbit polyclonal antibodies recognize both human and mouse Aβ and have been shown to be effective in Western, immunohistochemistry and ELISA applications. The antibodies detect <1 ng/ml protein by Western, and <1 pg/ml by ELISA.
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