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Corona Charged Aerosol Detector (CAD) offers a robust HPLC detection technology. HPLC column eluent is nebulized and the resulting droplets dry at ambient temperature producing analyte particles. A second stream of gas is positively charged as it passes a high-voltage, platinum corona wire. The charged gas collides with and transfers charges to the opposing stream of analyte particles. A negatively charged, low-voltage ion trap removes high-mobility particles while analyte particles transfer their charges to a collector. The charge transferred to the collector is in direct proportion to analyte mass. The technology is applicable for measuring virtually any non- or semi-volatile compound such as drug compounds, carbohydrates, steroids, proteins, lipids, peptides and sugars. The detector installs easily with any HPLC system and has a small footprint.© 2008 Advantage Business Media. All rights reserved.
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