Millipore Corporation
17 Cherry Hill Road
Danvers, MA, 01822
Website: http://www.millipore.com
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384-Well Filter Plates
Millipore 384-well MultiScreenHTS filter plates are offered for high throughput bioassays, including receptor-ligand binding and enzyme assays. Available with glass fiber or phosphocellulose (PH) paper, the filter plates’ automation compatibility increases throughput on a range of robots. In addition, the plates provide a direct scale-up solution from 96-well filter based assays. Plates with glass fiber FB or FC membrane are available for receptor-ligand binding assays. The assays can be performed directly in the filter plates, conserving reagents and reducing radioactive waste. Performing the assay in one plate minimizes manipulations and eliminates the need for separate incubation plates. Designed for coincidence scintillation counting, quantitative data can be collected at very low specific activity levels, and for challenging tritiated (3H) ligands. Kinase assays are a critical step in both lead identification and characterization processes. The PH paper retains peptide substrates while the plate design allows rapid washing to remove the unreacted, labeled ATP (Adenosine Triphosphate). PH paper provides low background and discrimination between drug target and non-hits.
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