Biomarker Assays


Two assays for quantitative biomarker analysis are offered for the Sequenom Inc. MassARRAY genetic analysis system. The EpiTYPER assay is an enabling tool for DNA methylation marker research. DNA methylation markers are useful because of their correlation to gene activity. High levels of cytosine methylation in genomic regions, such areas being referred to as CpG islands, are often associated with decreased or completely inhibited gene expression. Researchers believe that DNA methylation patterns play an important role in early cancer detection and prognosis. The EpiTYPER assay assists cancer geneticists and other researchers by providing quantitative results in the form of methylation ratios in targeted genomic regions. The QGE iPLEX multiplex assay, for quantitative gene expression analysis, provides simultaneous quantitative results for 20 or more genes per reaction thus minimizing costs per data point. Sequenom, Inc.619-350-0345www.sequenom.com



 


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