The Autolab ESPRIT surface plasmon resonance (SPR) system offers the option of simultaneous electrochemical and SPR measurements. Dual channels, one for samples and one for reference, are provided. An integrated autosampler allows samples to be handled manually and with automated methods, either preprogrammed or customized. Additional electrochemical techniques include cyclic voltammetry and impedance spectroscopy when used with an Autolab electrochemical systems.