ProteasMAX Surfactant enhances the enzymatic performance of trypsin and other proteases in preparation for analysis by mass spectrometry or liquid chromatography. The surfactant enables scientists to obtain a more complete digestion prior to protein analysis, resulting in more accurate data in a shorter time, and reduced risk of sample degradation. The product improves protein digestion by exposing cleavage sites usually inaccessible due to secondary or tertiary structure; increases sample recovery from gels; reduces standard protein digestion time to just three hours; and enhances protein solubilization at room temperature, which means that high temperatures (and precipitation) can be avoided, even for complex proteins. Because ProteasMAX degrades during the digestion reaction, researchers can proceed directly to analysis of peptides by mass spectrometry without additional inactivation steps. The reagent is compatible with existing protocols for 1 or 2D in-gel digestion of a purified protein or the digestion of complex protein samples by 2D LC-MS/MS. Promega Corp., 800-356-9526, www.promega.com.