Protein Enrichment Kits
Featured In: Protein Purification
Monday, December 17, 2007
ProteoMiner kits enable researchers to concentrate and enrich low- and medium-abundance proteins that cannot be detected through traditional methods. The kits are compatible with a variety of sample types and can be used with most downstream protein analysis techniques including one- or two-dimensional gel electrophoresis, chromatography, and surface-enhanced laser desorption/ionization. The bead-based technology employed uses a diverse library of combinatorial peptide ligands to simultaneously dilute high-abundance proteins and concentrate low-abundance proteins. When a complex biological sample is applied to the beads, high-abundance proteins saturate their high affinity ligand(s), and excess protein is washed away. In contrast, low-abundance proteins are concentrated on their specific affinity ligand(s).