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Brain Metabolism Linked to Fluid Intelligence

March 31, 2016 | by Bevin Fletcher, Associate Editor | Comments

The human brain needs a large amount of energy to function properly, and researchers at the University of Illinois have reported in a new study that the health of brain metabolism in young adults may predict fluid intelligence – the capacity to solve unusual logic-based problems in novel situations.

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Use of an Electronic Pipette to Ensure Reliable, Reproducible Results with Repetitive Pipetting

March 23, 2016 10:24 am | by Nora Meneceur, Product Manager and Beatrice Guieu-Presle, Test Laboratory Manager, Gilson | Comments

Advances in technology are pushing the limits of sample throughput for qPCR, ELISAs, and many other core biological assays. This has the potential to greatly improve lab efficiency but also create process bottlenecks if not managed correctly. With the proper tools, scientists can tackle the greater number of samples and the levels of repetition this sample processing requires, while ensuring reproducibility of their results.

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Jennifer Doudna Honored with For Women in Science Award

March 18, 2016 10:57 am | by Bevin Fletcher, Associate Editor | Comments

Jennifer Doudna, Ph.D., one of the brains behind the revolutionary CRISPR-Cas9 gene editing technology told Bioscience Technology about her early exploration into science and where she thinks CRISPR will have the biggest impact. 

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Utilization of the Crowd for Medical Research

March 2, 2016 9:09 am | by Sujay Jadhav, CEO, goBalto | Comments

Recently, some have begun to explore the utilization of the crowd for various purposes in medical research, including fundraising as well as crowdsourcing for intellectual analyses and insights. 

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Finding the Information ‘Needle in a Haystack’

February 19, 2016 11:07 am | by Laurent Fanichet, Vice President of Marketing, Sinequa | Comments

Digging through volumes of pharmaceutical data in any form, be that of lab reports, experimental results, clinical trial reports, scientific publications, patent filings, to even emails is a gargantuan task.  The data may deal with diseases, genes, drugs, active agents and mechanisms of action and can be textual, structured data like molecule structures, formulae, SAS data sets from clinical trials, curves, diagrams, and more. 

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Scientists Assess Anthropogenic Effects on Climate Change

January 21, 2016 9:40 am | by Greg Watry, Digital Reporter | Comments

Melting snow ice and glaciers in Europe, changes to the terrestrial ecosystem in Asia, and wildfires in the state of Alaska.

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How Can Antibodies Ensure Your Research Stands the Test of Time?

January 20, 2016 8:52 am | by Poulomi Acharya, Global Product Manager, Bio-Rad Laboratories | Comments

Academic researchers work on average more than 60 hours per week, according to a Inside Higher Ed survey. Why? Many scientists feel the sacrifice is worth it, as they devote their lives to an overwhelmingly important and meaningful human pursuit. Why then would researchers jeopardize the legitimacy of their work over results that could be potentially irreproducible?

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Genomics, Cannabidiols Drive Epilepsy Research

January 19, 2016 8:46 am | by Bevin Fletcher, Associate Editor | Comments

Scientists recently converged in Philadelphia for the American Epilepsy Society’s (AES) 69th Annual Meeting, touting new studies and insights in the field of epilepsy. Researchers discussed new findings, including personalized medicine, and the promise of Cannabidiol in human and animal studies.

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Six Reasons to Add Object Storage to Your Genomics Lexicon

December 15, 2015 8:42 am | by Claire Giordano, Senior Director of Emerging Storage Markets, Quantum | Comments

Object storage has been around for some time, but the technology is now gaining more and more traction in life sciences. This article outlines six reasons that organizations should add object storage to their genomics lexicon.

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Fighting the US STEM Crisis With All-Day Robotics, Endoscopy, and Monster-Making

December 14, 2015 8:53 am | by Cynthia Fox, Science Writer | Comments

Michael Zigman, founder of i2 Learning and friend Ethan Berman, a technology entrepreneur formerly with JP Morgan, launched a highly innovative, hands-on STEM (science, technology, engineering, math) summer program in 2013 for middle schoolers in two empty schools. The i2 crew decided to expand into the school day.

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Realizing the Promise: NGS in Precision Cancer Medicine

December 1, 2015 8:45 am | by Dr. Stephen Archibald, Director of Communications, Oxford Gene Technology | Comments

Precision cancer medicine is driven by the latest advances in genetic technologies. In light of falling costs and increased accessibility sparking a greater uptake of next generation sequencing (NGS), Clinical Scientists Dr. Matthew Smith and Dr. George Burghel discussed the strengths and challenges of this approach.  

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Chelsea, Hillary, and Top Researchers Make Global Push For Girls In Science

November 24, 2015 9:22 am | by Cynthia Fox, Science Writer | Comments

 For an intense global program called 1000 Girls-1000 Futures, the NYAS recently sought 60 women willing to devote a full year to mentees from Mexico alone. NYAS head Ellis Rubenstein told the presser Mexican supporters were “terrified” no one would step up. But 170 woman researchers—and counting— stepped up worldwide.  

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50 Years Later, Consortium Looks for Freeze-drying Overhaul

November 19, 2015 8:56 am | by Bevin Fletcher, Associate Editor | Comments

Lyophilization, also known as freeze-drying, is a critical technology for the food industry, pharmaceuticals and biotech. However, the process, which removes water from products at low temperatures and low pressure, is expensive, time-consuming and has remained unchanged for the last 50 years. 

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Immunotherapy: The Need for Immunocompetent Models

November 6, 2015 8:38 am | by Qian Shi, Ph.D., Executive Director of Cancer Pharmacology, Crown Bioscience | Comments

There is a great unmet need for improved preclinical models, with functional immunity, to drive forward promising immunotherapy research in oncology and to enable the successful transition of immunotherapeutics from the laboratory to the clinic. The benefits these models can provide could drive the development of combination therapy, improving patient comfort and saving lives.

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Optimizing ELISA

November 5, 2015 8:59 am | by Rishi Porecha, Ph.D. | Comments

ELISA – Enzyme-Linked Immunosorbent Assay – is a commonly used biochemical technique for the evaluation of an antigen or antibody in a sample. This technique is used in a wide range of applications, including: clinical diagnostics, plant pathology, the detection of food allergens and drug screening.

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Exchanging Out TFA from Synthetic Peptide Preparations: Why it’s Important and How to do it Effectively

November 4, 2015 9:02 am | by Ivona Strug and Timothy Nadler, EMD Millipore Corporation | Comments

In this case study, we show how Trifluoroacetate (TFA) salts hamper peptide analysis by FTIR spectroscopy. Subsequently, we present a detailed method by which TFA can be exchanged for HCl, with the goal of increasing the reproducibility and accuracy of peptide-based assays.

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