Precision cancer medicine is driven by the latest advances in genetic technologies. In light of falling costs and increased accessibility sparking a greater uptake of next generation sequencing (NGS), Clinical Scientists Dr. Matthew Smith and Dr. George Burghel discussed the strengths and challenges of this approach.
There is a great unmet need for improved preclinical models, with functional immunity, to drive...
Exchanging Out TFA from Synthetic Peptide Preparations: Why it’s Important and How to do it EffectivelyNovember 4, 2015 9:02 am | by Ivona Strug and Timothy Nadler, EMD Millipore Corporation | Comments
In this case study, we show how Trifluoroacetate (TFA) salts hamper peptide analysis by FTIR...
Early metastatic breast cancer cells are, strikingly, far more like stem cells than other tumor...
Melting snow ice and glaciers in Europe, changes to the terrestrial ecosystem in Asia, and wildfires in the state of Alaska.
Academic researchers work on average more than 60 hours per week, according to a Inside Higher Ed survey. Why? Many scientists feel the sacrifice is worth it, as they devote their lives to an overwhelmingly important and meaningful human pursuit. Why then would researchers jeopardize the legitimacy of their work over results that could be potentially irreproducible?
Scientists recently converged in Philadelphia for the American Epilepsy Society’s (AES) 69th Annual Meeting, touting new studies and insights in the field of epilepsy. Researchers discussed new findings, including personalized medicine, and the promise of Cannabidiol in human and animal studies.
Object storage has been around for some time, but the technology is now gaining more and more traction in life sciences. This article outlines six reasons that organizations should add object storage to their genomics lexicon.
Michael Zigman, founder of i2 Learning and friend Ethan Berman, a technology entrepreneur formerly with JP Morgan, launched a highly innovative, hands-on STEM (science, technology, engineering, math) summer program in 2013 for middle schoolers in two empty schools. The i2 crew decided to expand into the school day.
For an intense global program called 1000 Girls-1000 Futures, the NYAS recently sought 60 women willing to devote a full year to mentees from Mexico alone. NYAS head Ellis Rubenstein told the presser Mexican supporters were “terrified” no one would step up. But 170 woman researchers—and counting— stepped up worldwide.
Lyophilization, also known as freeze-drying, is a critical technology for the food industry, pharmaceuticals and biotech. However, the process, which removes water from products at low temperatures and low pressure, is expensive, time-consuming and has remained unchanged for the last 50 years.
ELISA – Enzyme-Linked Immunosorbent Assay – is a commonly used biochemical technique for the evaluation of an antigen or antibody in a sample. This technique is used in a wide range of applications, including: clinical diagnostics, plant pathology, the detection of food allergens and drug screening.
Understanding drug safety is a tricky thing. The use of direct-to-patient (or consumer) registry data is a new approach, and one that is quite different from the highly controlled world of clinical trials. Some worry about whether patients will be accurate and honest reporters. Will these patients be reliable, and will they provide clinically generalizable information?
Like a bad teenager, in 95 percent of all amyotrophic lateral sclerosis (ALS) cases, a protein called TDP-43 leaves its home— the nucleus of motor neuron cells—to congregate, in suspect fashion, in the cytoplasm. In a study published in Science this summer, the Johns Hopkins University (JHU) team of pathologist Phillip Wong, Ph.D., offered new insight into this molecular rebellion.
Embryonic stem (ES) cell-like stem cells made from adult cells—and morphed into eye cells—are not rejected by the immune system, according to “humanized mouse” data in Cell Stem Cell.
The technique of Surface Plasmon Resonance (SPR), allows scientists to monitor biomolecular binding interactions label-free, in real-time and using automation. For those of you thinking about, or planning on, using SPR, this article offers insights on how to use the technique successfully, gained from working with this technique for a number of years.
The National Institutes of Health has awarded 13 grants for a landmark, multi-site study that will follow 10,000 children over 10 years to observe how substance use affects the brain, and the findings could help guide important public policy decisions.
Young female and male Johns Hopkins University (JHU) Medical School M.D.’s and Ph.D.’s receive equal numbers of key National Institutes of Health (NIH) grants, says a recent Journal of Women’s Health study.
The agency wants more insight into the company's data and marketing materials supporting the effectiveness of their product.