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Realizing the Promise: NGS in Precision Cancer Medicine

December 1, 2015 | by Dr. Stephen Archibald, Director of Communications, Oxford Gene Technology | Comments

Precision cancer medicine is driven by the latest advances in genetic technologies. In light of falling costs and increased accessibility sparking a greater uptake of next generation sequencing (NGS), Clinical Scientists Dr. Matthew Smith and Dr. George Burghel discussed the strengths and challenges of this approach.

 

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Scientists Assess Anthropogenic Effects on Climate Change

January 21, 2016 9:40 am | by Greg Watry, Digital Reporter | Comments

Melting snow ice and glaciers in Europe, changes to the terrestrial ecosystem in Asia, and wildfires in the state of Alaska.

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How Can Antibodies Ensure Your Research Stands the Test of Time?

January 20, 2016 8:52 am | by Poulomi Acharya, Global Product Manager, Bio-Rad Laboratories | Comments

Academic researchers work on average more than 60 hours per week, according to a Inside Higher Ed survey. Why? Many scientists feel the sacrifice is worth it, as they devote their lives to an overwhelmingly important and meaningful human pursuit. Why then would researchers jeopardize the legitimacy of their work over results that could be potentially irreproducible?

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Genomics, Cannabidiols Drive Epilepsy Research

January 19, 2016 8:46 am | by Bevin Fletcher, Associate Editor | Comments

Scientists recently converged in Philadelphia for the American Epilepsy Society’s (AES) 69th Annual Meeting, touting new studies and insights in the field of epilepsy. Researchers discussed new findings, including personalized medicine, and the promise of Cannabidiol in human and animal studies.

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Six Reasons to Add Object Storage to Your Genomics Lexicon

December 15, 2015 8:42 am | by Claire Giordano, Senior Director of Emerging Storage Markets, Quantum | Comments

Object storage has been around for some time, but the technology is now gaining more and more traction in life sciences. This article outlines six reasons that organizations should add object storage to their genomics lexicon.

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Fighting the US STEM Crisis With All-Day Robotics, Endoscopy, and Monster-Making

December 14, 2015 8:53 am | by Cynthia Fox, Science Writer | Comments

Michael Zigman, founder of i2 Learning and friend Ethan Berman, a technology entrepreneur formerly with JP Morgan, launched a highly innovative, hands-on STEM (science, technology, engineering, math) summer program in 2013 for middle schoolers in two empty schools. The i2 crew decided to expand into the school day.

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Chelsea, Hillary, and Top Researchers Make Global Push For Girls In Science

November 24, 2015 9:22 am | by Cynthia Fox, Science Writer | Comments

 For an intense global program called 1000 Girls-1000 Futures, the NYAS recently sought 60 women willing to devote a full year to mentees from Mexico alone. NYAS head Ellis Rubenstein told the presser Mexican supporters were “terrified” no one would step up. But 170 woman researchers—and counting— stepped up worldwide.  

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50 Years Later, Consortium Looks for Freeze-drying Overhaul

November 19, 2015 8:56 am | by Bevin Fletcher, Associate Editor | Comments

Lyophilization, also known as freeze-drying, is a critical technology for the food industry, pharmaceuticals and biotech. However, the process, which removes water from products at low temperatures and low pressure, is expensive, time-consuming and has remained unchanged for the last 50 years. 

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Optimizing ELISA

November 5, 2015 8:59 am | by Rishi Porecha, Ph.D. | Comments

ELISA – Enzyme-Linked Immunosorbent Assay – is a commonly used biochemical technique for the evaluation of an antigen or antibody in a sample. This technique is used in a wide range of applications, including: clinical diagnostics, plant pathology, the detection of food allergens and drug screening.

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Direct-to-Patient Registries: A New Approach to Pharmacovigilance

October 28, 2015 9:38 am | by Nancy Dreyer, MPH, Ph.D., Global Chief of Scientific Affairs and Michelle Leavy, MPH, Manager, Health Policy, Quintiles | Comments

Understanding drug safety is a tricky thing. The use of direct-to-patient (or consumer) registry data is a new approach, and one that is quite different from the highly controlled world of clinical trials. Some worry about whether patients will be accurate and honest reporters. Will these patients be reliable, and will they provide clinically generalizable information?

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Role Found for Critical Gene in 95% of ALS

October 22, 2015 9:10 am | by Cynthia Fox, Science Writer | Comments

Like a bad teenager, in 95 percent of all amyotrophic lateral sclerosis (ALS) cases, a protein called TDP-43 leaves its home— the nucleus of motor neuron cells—to congregate, in suspect fashion, in the cytoplasm. In a study published in Science this summer, the Johns Hopkins University (JHU) team of pathologist Phillip Wong, Ph.D., offered new insight into this molecular rebellion.

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Some Stem Cells Are Rejected, Some Aren’t, Says iPSC Work

October 21, 2015 9:38 am | by Cynthia Fox, Science Writer | Comments

Embryonic stem (ES) cell-like stem cells made from adult cells—and morphed into eye cells—are not rejected by the immune system, according to “humanized mouse” data in Cell Stem Cell.

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How to Make Your Surface Plasmon Resonance Experiments Successful

October 14, 2015 8:56 am | by Mary M. Murphy, Ph.D., Applications Scientist, Reichert Life Sciences | Comments

The technique of Surface Plasmon Resonance (SPR), allows scientists to monitor biomolecular binding interactions label-free, in real-time and using automation. For those of you thinking about, or planning on, using SPR, this article offers insights on how to use the technique successfully, gained from working with this technique for a number of years.

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A Look at Landmark NIH Study on Substance Use and the Developing Brain

October 8, 2015 9:21 am | by Bevin Fletcher, Associate Editor | Comments

The National Institutes of Health has awarded 13 grants for a landmark, multi-site study that will follow 10,000 children over 10 years to observe how substance use affects the brain, and the findings could help guide important public policy decisions.

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Johns Hopkins Women and Men Score Equal Numbers of Key NIH Grants

October 2, 2015 9:27 am | by Cynthia Fox, Science Writer | Comments

Young female and male Johns Hopkins University (JHU) Medical School M.D.’s and Ph.D.’s receive equal numbers of key National Institutes of Health (NIH) grants, says a recent Journal of Women’s Health study.

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FDA Warns Startup Selling Suspicious Blood-Based Cancer Tests

October 1, 2015 8:26 am | by Ryan Bushey, Associate Editor | Comments

The agency wants more insight into the company's data and marketing materials supporting the effectiveness of their product.

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