by Elizabeth Tolchin Optical mapping of DNA derived from brain tumors (oligodendrogliomas) could help pinpoint the genetic variation that determines the effectiveness of drug therapies in patients, according to researchers.
by Elizabeth Tolchin Are pseudogenes important for understanding the human genome? Yes, says a group from Yale who catalogued 8,000 processed pseudogenes in the human genome.
by Tariq Malik, a freelance writer based in Queens, N.Y. An alliance between Pfizer Inc., New York, and the discovery chemistry provider ChemBridge Research Laboratories LLC (CRL), San Diego, has grown beyond its initial goal to produce advanced screening libraries for the global pharmaceutical giant.
by Don Monroe, PhD The US Food and Drug Administration reported in January what it called a rebound in approval of innovative drugs in 2003.
Phospho-ERK1/ERK2 DuoSet® IC ELISA Development System kits (R&D Systems) provide an alternative to Western blots for intracellular factors involved in signal transduction, apoptosis, and transcription.
Anti-human TCR V?12.1 monoclonal antibody is for validated applications including flow cytometry, immunoprecipitation, frozen tissue staining, and T cell activation. Anti-human TCR V?6.
Miltenyi Biotec has announced the release of several new MACS® products for the isolation of untouched human B cells.
The Z'-LYTE assay platform (Invitrogen Corp.) provides a fluorescence-based biochemical
Diagnostic Systems Laboratories, Inc. has launched an Inhibin B ELISA. It is specific for dimeric Inhibin B, does not require sample pretreatment, and can be fully automated on open-platform microplate systems.
Pefakit® TAFI is a highly specific, 2-step chromogenic assay for the measurement of TAFI (Thrombin Activatable Fibrinolysis Inhibitor) in plasma.
HSP27 [pS82] phosphoELISA is sensitive to 1,000 cells/well, demonstrated with HeLa cell lysates. Additional validated cell lines include THP-1, HT1080, Jurkat and 293 cells.
HDAC8 Colorimetric/Fluorometric Activity Assay/Drug Discovery Kit is HTS-friendly assay and allows real-time monitoring of HDAC activity. This is made possible by HDAC-TRAC substrate and buffer, which also enables a choice of either colorimetric or fluorometric detection.
BioFX's chemiluminescent substrates are used in immunoassay and immunoblotting applications. The reagents are intensified and the signal duration increased by proprietary enhancers.
ProteomeLab IgG purity/heterogeneity assay (Beckman Coulter) is offered in kit format with a validated standard operating protocol (SOP).
STEAP (Six-transmembrane epithelial antigen of the prostate) is a prostate-specific cell surface antigen that is highly expressed in human prostate cancers. STEAP is unique among cell surface prostate antigens in its potential function as a channel or transport protein.