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siRNA Transfection Reagent (2569)

January 29, 2004 3:52 am | Articles | Comments

GeneEraser™ siRNA transfection reagent is designed for transfection of siRNA into mammalian cells. This low-toxicity reagent has demonstrated high transfection efficiency of siRNA in a variety of cell lines.

In Vitro Transcription System

January 29, 2004 3:52 am | Articles | Comments

T7 RiboMAX™ Express RNAi System (a,b,c) is an in vitro transcription system designed for producing milligram amounts of double-stranded RNA (dsRNA) in a short amount of time.

RNA Evaluation Kit

January 29, 2004 3:52 am | Articles | Comments

The RNA Inspector Kit evaluates RNA and cDNA for the presence of transcripts from 1 kb to 14 kb from human, mouse and rat tissues and cell lines. The kit evaluates RNA integrity and quality, the success of cDNA synthesis, and ensures full-length cDNA when constructing cDNA libraries.

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siRNA Intracellular Localization

January 29, 2004 3:52 am | Articles | Comments

Label IT® siRNA Tracker Intracellular Localization Kits directly label and deliver siRNA of individual design in an efficient, non-destructive manner, for in vitro tracking experiments.

RNA Transcription Kit

January 29, 2004 3:52 am | Articles | Comments

AmpliScribe™ T7- Flash ™ in vitro transcription kit produces high yields of RNA in a short reaction time. The standard 30 minute kit reaction produces 160 - 180 μg (8 -9 mg/ml) of RNA from 1 μg of DNA template. A 6-fold linear scale up produces >1 mg of RNA in just 30 minutes.

Drosophila RNAi Collection

January 29, 2004 3:52 am | Articles | Comments

The use of RNAi as a genetic tool in Drosophila is made easier through the availability of the Drosophila RNAi Collection, a set of over 7,000 DNA constructs ready for in vitro transcription. The collection consists of dsDNAs covering 50% of the Drosophila genome.

Lamin A/C siRNA/siAb Kit

January 29, 2004 3:52 am | Articles | Comments

The Lamin A/C siRNA/siAb Assay Kit provides a complete, validated assay for silencing a commonly expressed endogenous gene.

RNA From Regions Of Diseased Human Brains

January 29, 2004 3:52 am | Articles | Comments

High quality, DNA free total RNAs are isolated from more than 17 distinct regions of human brains from patients suffering from Alzheimer's, Parkinson's, and AEL. All tissues are ethically obtained and trained neuroanatomists dissect the specific brain regions.

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Targeted Drug and Gene Delivery with Microbubbles 1/28/04

January 28, 2004 11:33 am | Articles | Comments

by Elizabeth Tolchin A technique that uses ultrasound energy to create microbubbles inside specially treated liposomes and then directs the liposomes to specific targets may offer a new method for targeted gene therapy and drug delivery.

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Protein Modification Kills Cancer Cells 1/27/04

January 28, 2004 9:58 am | Articles | Comments

by Elizabeth Tolchin A recently discovered protein plays a role in preventing cell death when DNA damage occurs. Cells with DNA damage are able to remain alive, furthering the development of cancer.

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Companies Collaborate on Canadian Haplotype Map 1/26/04

January 26, 2004 11:59 am | Articles | Comments

by Elizabeth Tolchin Two companies plan to work together to create a Quebec Linkage Disequilibrium Map (QLDM) consisting of approximately 40,000 single-nucleotide polymorphisms (SNPs).

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Microarrays Support Reporter Assays for Antibacterial Drug Discovery 1/23/04

January 23, 2004 12:44 pm | Articles | Comments

by Elizabeth Tolchin Researchers demonstrated a new microarray-supported approach for developing pathway-specific assays for high-throughput screening of compound libraries.

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Finding the Return on Microarrays 1/22/04

January 22, 2004 11:52 am | Articles | Comments

by Elizabeth Tolchin Illumina Inc. recently announced two new Sentrix BeadChips for whole-genome expression profiling of multiple samples on a single chip. The new six-sample whole-genome BeadChip is to compete with microarray products that analyze one genome on a chip.

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HIP Chemical Genetic Screens Uncover Drug Targets 1/21/04

January 21, 2004 12:45 pm | Articles | Comments

by Elizabeth Tolchin Experiments with chemical genetic screens for finding new drug targets led to a method that uses a yeast culture to identify the gene products that functionally interact with small molecules and inhibit cell proliferation.

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Protein Crystallization With Minimal Frustration 1/20/04

January 20, 2004 12:27 pm | Articles | Comments

by Elizabeth Tolchin A new technique called enhanced amide hydrogen/deuterium-exchange mass spectrometry, or DXMS, promises to take some of the frustration out of protein crystallization.

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