Eppendorf LoBind microcentrifuge tubes are optimized for either proteomic or genomic (DNA/RNA) applications. Available in 0.5-, 1.5-, and 2.0-ml sizes, the tubes feature the Safe-Lock lid and contain no DNnase, RNase, human DNA, or PCR inhibitors.
Instrumentation, software, columns, and method protocols are integrated in this complete system for identification of proteins and biomarkers. A manual of optimized method protocols is included for each step of the MS-based proteomics workflow, from sample preparation to data analysis and reporting.
S+ArrayAnalyzer 2.0 microarray analysis software provides statisticians, computational biologists and informaticians with workflows for data access, QC data diagnostics, robust data preparation, rigorous statistical modeling and annotated graphical reporting.
SMACK 1.0 converts substructure and reaction queries expressed in MDL file formats to Daylight's SMARTS strings. It automatically optimizes SMARTS queries for pattern-matching performance both in terms of average search times and maximum search times.
Version 3.2 of the Validation Tool Kit includes two separate components, a software application and a full documentation package, that provide automated assistance and detailed guidance for both IQ and OQ.
Vector Xpression and Vector PathBlazer software bundle enables researchers to discover biological insights through a cycle of discovery. For example, identifying differences in transcript levels of many genes between normal vs.
Netezza Performance Server (NPS) tera-scale data warehouse includes data types specific to bioinformatics applications and integrates sequence analysis using BLAST with an SQL relational database.
Two software methods for studying protein-protein docking, ZDOCK, and RDOCK help researchers understand the action of therapeutically interesting proteins by predicting the manner in which two proteins interact at the atomic level. Most, if not all, proteins have interacting partners in a cell.
Thirteen databases have been introduced that contain measured ADME/Tox properties for a range of chemical compounds, covering seven endpoints including Blood Brain Barrier, Human Intestinal Absorption, log D, log P, Mutagenicity, Plasma-Protein Binding, and Water Solubility.
Nonlinear Dynamics Progenesis Discovery Informatics platform supports the gel-based component of the company's proteomic service offering. The product automates high-throughput gel analysis, data mining, and support of lab-based research.
GenomeQuestLive! genomic/proteomic sequence search service enables both functional and
Genstruct's Molecular Epistemics platform enables the identification of mechanisms of action for small molecule drugs, mechanisms of drug resistance and potential biological markers to support decision making on clinical compounds.
By Elizabeth Tolchin
FRET microscopy imaging is widely used to detect protein-protein interactions inside living cells. This application note describes the use of one and two-photon FRET and in characterizing the dimerization of C/EBP?
By Elizabeth Tolchin