The Library of Pharmacologically-Active Compounds (LOPAC 1280 ) is a collection of 1,280 characterized small ligands used for assay validation and orphan receptor characterization.
RNAi targets gene silencing, and is achieved in mammalian cells through the use of short interfering RNA molecules, or siRNAs. RNAi has accelerated the functional characterization of disease-relevant genes for drug discovery and basic research efforts.
Adiponectin (Acrp30), an adipocyte-specific secreted protein, circulates in plasma and plays a role in various physiological processes, such as energy homeostasis and obesity. Active recombinant human, mouse, and rat adiponectin was expressed using perspective adiponectin of cDNA.
VWR and VWR Signature heated and refrigerated circulators featuring enhanced electronics that allow intuitive, user-friendly programming and control.
Ambion, Inc. (Austin, Tex. and Cenix BioScience GmbH (Dresden, Germany) have announced that siRNA designs have been completed for more than 98% of all human, mouse, and rat genes listed in the public RefSeq database.
Barnstead/Thermolyne brand Cimarec® hot plates and stirring hot plates offer digital technology and enhanced safety features. High wattage boils liquids quickly. Digital microprocessor-controlled technology ensures repeatable, accurate temperatures.
Resin-bound oxidizing reagent, MP-TsO-TEMPO, for alcohol oxidation, assists medicinal chemists in increasing the diversity of targeted drug compounds.
The AutoGenprep 965, a completely automated 96 well format robotic system for DNA extraction, produces high yields of quality DNA at a very low cost per prep. The 965 was recently released with a protocols for whole blood and BAC/plasmid.
Biodesign International has recently added myostatin antibodies to its line of over 300 cytokine and growth factor products. Myostatin is a member of the transforming growth factor-beta (TGF-beta) family of secreted regulatory factors.
Orbit Digital Shakers are offered in six versions to accommodate a range of microplates, micro tubes, flat containers, dishes and culture flasks. The 3 mm models provide vigorous mixing of small volume samples like 96 well plates and micro tubes.
TaqPlus ® Maxx DNA polymerase is a blend of cloned Taq and Pfu DNA polymerases and Stratagene's exclusive ArchaeMaxx polymerase-enhancing factor. Together with an optimized buffer, this enzyme blend provides a high success rate.
The slide spinner quickly dries two microarray slides, and easily removes wash buffer prior to slide scanning. The device includes the centrifuge and two removable cassettes that conveniently trap all liquid.
MiniPrep bench-top lab, used with the new MagPrep(R) reagent kits, streamlines the DNA separation process, providing reproducible results at a fraction of the hands-on time of manual methods.
Long Tip Cone Finnpipette® Focus Pipette minimizes hand and arm strain during pipetting. Removable snap-on handle is available in large, medium and small, allowing the best fit for an individual's hand.
TTP LabTech has announced the comPOUND® Double-Density (D2) sample store, holds two shorter microtubes (0.35 ml instead of the standard 1.0 ml) in each hole of comPOUND's carousels, doubling capacity to 200,000 tubes.