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Patents Issued for DNA Delivery 1/9/04

January 9, 2004 12:30 pm | Articles | Comments

by Elizabeth Tolchin Vical Inc. received two U.S. Patents covering methods for using DNA to deliver biologically active proteins (No. 6,673,776), and a class of cationic lipids useful in gene delivery applications (No. 6,670,332).

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US Navy Tests DNA Vaccine Delivery System 1/8/04

January 8, 2004 12:22 pm | Articles | Comments

by Elizabeth Tolchin The Naval Medical Research Center (NMRC) plans to work with Inovio AS to conduct trials of Inovio's in vivo electroporation (EP) technology for delivery of DNA vaccines, as part of a Cooperative Research and Development Agreement (CRADA).

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Corn Gene Coordinates Meiosis 1/7/04

January 7, 2004 11:20 am | Articles | Comments

by Elizabeth Tolchin Biologists identified a mutant gene in maize that plays a role in meiosis. In the case of maize (or corn), the process is essential for producing the megagametophyte, which is the egg, and pollen, the equivalent to sperm in animals.

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HapMap Consortium Reveals Plans 1/6/04

January 6, 2004 7:35 am | Articles | Comments

by Elizabeth Tolchin After years of preparation, the International HapMap Consortium is providing detailed plans of the HapMap project, its effort to create a haplotype map for the human genome.

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Joint NCI/FDA Task Force Debuts First Initiatives 1/5/04

January 5, 2004 9:20 am | Articles | Comments

by Pam Holland-Moritz A joint oncology task force, by the US Food and Drug Administration (FDA) and the National Cancer Institute (NCI), rolled out the first two initiatives of their interagency agreement to share knowledge and resources in order to speed up the development of drugs to fight cancer.

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HemoPDB Directed at Blood Cell Diseases 12/29/03

December 29, 2003 8:34 am | Articles | Comments

by Elizabeth Tolchin A new database provides a searchable resource of genomic information related to leukemia and other blood disorders.

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FDA Approves Genetic Tests for Thrombophilia 12/23/03

December 23, 2003 11:59 am | Articles | Comments

by Elizabeth Tolchin A new set of polymerase chain reaction (PCR) tests that aid the diagnosis of patients with suspected thrombophilia, were approved by the US Food and Drug Administration.

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Lexicon Genetics Forms Neuroscience Alliance with Bristol-Myers Squibb 12/22/03

December 22, 2003 12:17 pm | Articles | Comments

by Elizabeth Tolchin A new alliance provides Bristol-Myers Squibb access to 13 drug targets in the current neuroscience pipeline of Lexicon Genetics Inc. BMS will also have first crack at future neuroscience discoveries.

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Assigning Functions Through Genetic Networks 12/19/03

December 19, 2003 10:59 am | Articles | Comments

by Elizabeth Tolchin Under the hypothesis that 'conserved coexpression' could serve as an indicator of gene function on a genomic level, a team from Israel developed a model for comparing gene expression data and genomic sequence information across several different species at once.

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Web Site Advises Best Sample Size 12/18/03

December 19, 2003 6:04 am | Articles | Comments

by Elizabeth Tolchin Some of the trial and error in designing gene expression experiments can be avoided, yielding faster and cheaper results, thanks to a new online resource.

Imaged Virus Reveals Production Mechanism 12/17/03

December 17, 2003 11:16 am | Articles | Comments

by Elizabeth Tolchin Cryo-electron microscopy helped determine the structure of a reovirus (respiratory enteric orphan virus) down to the 7.6-angstrom scale. The structure provides a clearer understanding of how the reovirus reproduces in cells.

Intoxication Controlled by "Slowpoke" Gene 12/16/03

December 16, 2003 10:22 am | Articles | Comments

by Elizabeth Tolchin Whether you toast your holiday celebrations with eggnog, champagne, or Manischewitz wine, you might expect the alcohol in these beverages to have an intoxicating effect. However, that may not always be true.

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Knowledge Management Made Free 12/15/03

December 15, 2003 12:17 pm | Articles | Comments

by Elizabeth Tolchin Software developer 3rd Millennium is releasing its Data Centric Knowledge Management System for biotech and pharmaceutical R&D to the public. The software, which allows the centralization and sharing of research data, can now be downloaded for free.

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Mouse Model Achieved for Pancreatic Cancer 12/12/03

December 12, 2003 12:00 pm | Articles | Comments

by Elizabeth Tolchin Boston researchers successfully created a mouse model for pancreatic cancer that approximates the behavior of the disease in humans.

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Alzheimer's Research Thriving, Says Report 12/11/03

December 11, 2003 8:17 am | Articles | Comments

by Elizabeth Tolchin A new report by market consultants Frost & Sullivan examines the US market for Alzheimer's disease drugs over the next five to seven years and finds that despite many setbacks, Alzheimer drug research and development is thriving.

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