by Elizabeth Tolchin MicroRNAs are frequently located in cancer-associated regions of the genome and can act as both tumor suppressor genes and oncogenes, according to a new study. The association could lead to the use of microRNAs in cancer treatment.
by Elizabeth Tolchin An assay technology for screening and select compounds that regulate immune responses developed by the University of British Columbia, Vancouver, Canada, was licensed recently to the Canadian company GeneMax Pharmaceuticals Inc., also in Vancouver.
by Elizabeth Tolchin Catalyst Biosciences Inc., San Francisco, a biotechnology start-up company focusing on the engineering of recombinant proteases as therapeutics in the areas of cancer and inflammation, recently licensed a method for rapidly determining the substrate specificity of a protease from the University of California, San Francisco (UCSF).
The Mid-Size Store from REMP is a fully automated sample storage and retrieval system. Unit size (32 10× 1110× 92 should allow it to fit in most existing laboratory spaces. Modular design allows capacity options of 20,400 MTP, 10,200 DWP or 392,700 vials (4 ml).
GenePlate® HT , a high-throughput, 384-well-format, automation-friendly mRNA isolation plate, facilitates fast, sensitive, reproducible isolation of mRNA from cell culture and tissue sources.
TekBench-SP is a fully automated liquid handling platform for the processing of tube- and plate-based samples in an inert environment, providing protection from factors known to compromise sample integrity and stability (oxygen, moisture, light, dust).
The CRS Mini DM Workstation is a scalable and reliable automation platform for automating ELISA and other biochemical assays. Modular design allows the system to expand easily by adding or swapping instruments and storage as assay and throughput requirements change.
MultiScreen HTS filter plates were developed specifically for use with automated workstations. One-piece plate design facilitates use with robotic gripper arms and stackers. Rigid sidewalls provide ample surface to accommodate bar code labels. Removable underdrain allows easy membrane access.
Rotanta 46 RSC refrigerated, robotic centrifuge features pc control and rotor positioning. Controlled by remote optical data transmission, it automatically performs routine laboratory tasks. If needed, all functions can be controlled manually via control panel.
Eppendorf ep Motion 5070 liquid handling workstation enables rapid and reproducible liquid handling through automated pipetting, dispensing and dispensing variants. Sequences and protocols that had been carried out manually can be transferred to the system.
Bio-Tek Instruments has expanded its line of μFill bulk reagent dispensers to with a unit that dispenses into 24-well plates with an easily adapted manifold designed specifically for cell-based applications.
AcroPrep 384 multi-well filter plate uses patented technology to eliminate lateral cross contamination by individually sealing each well. Laboratories can reliably process 384 samples in minutes, increase output and identify promising drug targets to treat diseases.
by Elizabeth Tolchin Acknowledging the importance of model organisms in pharmaceutical research, Novartis appointed Susan Gasser, PhD, to director of the Friedrich Miescher Institute (FMI) in Basel, Switzerland.
The number of PCR-based methods for plant molecular research has increased dramatically. Application of these methods alone, or in combination with other tools, range from marker assisted selection, molecular mapping, varietal identification and phylogeny research to genomics and chip technology.
by Elizabeth Tolchin Optical mapping of DNA derived from brain tumors (oligodendrogliomas) could help pinpoint the genetic variation that determines the effectiveness of drug therapies in patients, according to researchers.