Preclinical oncology compound from J&JPRD
A range of sterilization-resistant laboratory labels are available for wet, dry and radiation sterilization processes.
Three M.O.M. (Mouse-on-Mouse) kits are offered for the localization of mouse primary antibodies on mouse tissue sections. The kits allow mouse primary antibodies to be stained while avoiding interfering background due to the detection reagents binding endogenous mouse antibody.
Cardiac related antibody and antigen line offers numerous monoclonals specific to the human cardiac isoform of Troponin I (cTnI). These antibodies have been characterized by Western blot for reactivity with Troponin I from different animal species.
Signaling research line includes antibodies for the Akt pathway, cell cycle and Checkpoint control, cytokines, DNA damage, the NfkB pathway and for ubiquitin.
Expanded line of iso-IHC Core kits come with the components required for performing iso-IHC, except the substrate-chromogen system, which the user can select from the Core Kit Accessories. Users have the freedom to work with the chromogenic system of choice.
Caspase-Glo 8 and Caspase-Glo 9 assays offer sensitive apoptosis detection. The homogeneous assay protocol for Caspase 8 & 9 provides results in 20 minutes.
Human IL-2 and Bovine TNF alpha Screening Sets are offered for development of 5 colorimetric ELISA plates each.
Cell Cycle Assay (Guava Technologies, Inc.) incorporates staining reagents pre-combined in a single optimized format, eliminating reagent preparation following cell fixation. Protocols are offered for use with either individual tubes or 96-well microplates, minimizing assay development time.
Anti-mPDCA-1 antibodies provide specific detection and isolation of murine plasmacytoid dendritic cells (mPDCs).
Lightspeed kinase assays, quenching fluorescence-based assays for drug discovery, are offered for PKCa (diabetes and leukemia), Akt-1 (cancer), Src (cancer) and p38a (leukemia and lymphoma).
Purified monoclonal antibody raised against human Interleukin-19 is available from R&D Systems. IL-19 is a novel member of the multifunctional IL-10 family. It is secreted as a monomer that contains a unique bundle of seven amphipathic helices.
CytoScan-LDH measures cytosolic enzyme lactate dehydrogenase (LDH) release as cells die. Released LDH is measured with a color producing diaphorase linked tetrazolium salt reaction. The amount of color produced is proportional to the number of cell deaths.
BD Falcon 96-Multiwell Insert System is a cell culture insert platform suitable for both manual and robotic screening of compounds in cell-based assays.
Ghrelin is a 28 amino acid peptide synthesized in the stomach that acts to stimulate food intake and help maintain energy homeostasis. Post-translational modification by n-octanoylation at serine 3 is essential for biological activity.