A new target of the inflammatory process
Visualizing prions as they interact
Phase I trial shows safety and promise
Because proteins perform the vast majority of cellular functions, it is critical for cells to regulate protein levels precisely. While gene expression is a multi-step process in which DNA information is copied first into RNA (transcription) and then translated into protein, regulation of specific protein levels is accomplished primarily through control of transcription
Activating resident stem cells to repair tissue
Protocol standardization and data management
Signaling for Stem Cells By comparing two signaling networks, scientists, in a recent issue of
Crystal structures reveal RNA binding sites
Mapping Genetic Variants in the MHC Region of the Genome
Researchers anticipate entry into biomarker discovery
Interest in characterizing novel proteins has led to an explosion in gene expression techniques. Whether used for therapy, experimentation, or biomanufacturing, gene expression is about producing proteins.
Terminator Exonuclease is a 5'-3' exonuclease that digests RNA with a 5'-phosphate such as prokaryotic 16S and 23S rRNA. Primary prokaryotic RNA transcripts (mRNAs) with a 5'-triphosphate are resistant to degradation.
RNeasy kits (Qiagen, Inc.) facilitate purification of pure, intact microRNA. Two protocols that work with existing RNeasy Kits are available.
Four reagents kits are offered for quantitative pcr and reverse transcription pcr. &GO Mastermixes simplify real-time analysis of DNA, cDNA and RNA and are supplied as complete 5× mixes, a format that minimizes pipetting and the potential for contamination.