Microarray technology has come a long way since Affymax, predecessor to Affymetrix (Santa Clara, CA), introduced polypeptide arrays in the late 1980s. Today's gene, protein, and tissue arrays have evolved from research curiosities to the experimental platform of choice for many life scientists and clinical researchers - something akin to high-tech, ultraminiaturized microtiter plates.
Cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) Targeted Mutation Mouse models are offered for investigating the role of cyclooxygenases in inflammatory diseases. COX Targeted Mutation mice have disruptions in one of the two Pts (protaglandin-endoperoxide synthase) genes.
Optronics has introduced automated 3-Pass color imaging technology with resolution up to 12 million pixels for their QuantiFire, MacroFire monochrome and MicroFire monochrome quantitative cameras.
Ratio:Matic Series Dual Head Dispensers and Metering Pumps provide dual channel fluid control for a range of lab applications. The pumps consist of two FMI pump heads direct coupled to a single variable speed drive.
New antibodies are offered for studying ER stress-related apoptosis, including antibodies to ATF6, BAP31, Caspase-12, CHOP, TRAF2 and BiP/GRP78.
Ascentis HPLC columns feature C18 and RP-Amide phases and combine proprietary bonding chemistry, unique end-capping and high purity silica to create what the company calls Surface-Optimized Technology. High surface coverage provides maximum HPLC performance.
Gen-Elute Five-Minute Plasmid Miniprep Kit relies on two technologies. The first is a lysis chemistry that enables DNA purification directly from an overnight culture. The sntadard miniprep steps of pelleting cells and neutralizing and clearing the lysate are eliminated.
Two dozen new antibodies, inhibitors, enzymes and related products have been added to a line of reagents for Toll-like Receptor (TLR) signaling and inflammation research, including six nex activators for TLR4.
Posi-RAM Model 3 is a small, complete continuous-flow detector for positron emitters. The analytical positron counter incorporates two BGO crystal/photomultiplier detectors operating in coincidence. Noise and detector backgrounds are virtually eliminated, resulting in system background of <20 cpm.
Mighty Mix DNA Ligation Kit, a one-solution, premixed kit, provides efficient ligations, particularly for blunt-end ligation and TA cloning. The single solution reagent simplifies reaction assembly, and minimizes the risk of contamination by eliminating pipetting steps.
BD Phosphopeptide Enrichment Spin Columns enhance detection of phosphorylated peptides. Kits include optimized buffers and a simple purification protocol for peptide phosphorylation studies.
Purasil flash chromatography silica gel is pure and has minimal fines, enabling fast separations and high resolution. The product is available in particle sizes ranges 7-230 and 230-400 mesh. Consistent particle size, pore diameter and surface area result in reproducible results.
LA Taq Hot Start is designed specifically for PCR amplification of long (up to 43 kb) DNA fragments. The product contains LA Taq , which possesses 3’-> 5’ exonuclease activity and provides high fidelity (6.5×), plus a neutralizing monoclonal antibody to Taq .
Biotinylated anti-polyhistidine antibody is offered for use in Western blot detection of fusion proteins tagged with 6× histidine. The antibody is raised in goat against a synthetic 6× His peptide, affinity purified and optimally labeled with biotin.
PhoenIX Filter Maxiprep Kit eliminates the need for centrifugation of bacterial lysate. A solid-phase column with patented ion exchange resin optimizes purification and enhances the degree of separation between different biomolecules.