Bio-Rad Laboratories, Inc. has announced six bead-based phosphoprotein assays for its Bio-Plex suspension array system. The products include: phospho-p70 S6 kinase, phospho-p90RSK, phospho-STAT2 and phospho-TrkA, total Akt, and total p90RSK.
Cytomat 44 automated storage module is a compact system designed to provide stable microplate storage conditions and to maximize compound integrity.
ExplorerPLS Automated Microwave Reaction Workstation is offered for speciation studies in analytical chemistry, as well as discovery or optimization of drug candidates in medicinal chemistry. A 24-sample deck with interchangeable racks maximizes throughput.
HiPerFect Transfection Reagent is offered for the transfection of eukaryotic cells with siRNA, and can be used with low siRNA concentrations. Transfection of the lowest effective siRNA concentration minimizes the likelihood of off-target effects.
The Biomek FX ADMETox Workstation, for in vitro drug permeability measurements, is a validated system that automates the PAMPA (Parallel Artificial Membrane Permeability Analysis) method for the determination of passive absorption of a drug candidate through an artificial lipid membrane.
Millipore 384-well MultiScreen HTS filter plates are offered for high throughput bioassays, including receptor-ligand binding and enzyme assays. Available with glass fiber or phosphocellulose (PH) paper, the filter plates’ automation compatibility increases throughput on a range of robots.
Trevigen has introduced the E-3 Western assay system. The methodology utilizes free solution pulsed electrophoresis in specially formulated buffers to quickly move charged protein molecules in solution. The process establishes the rapid formation of stable and highly specific immune complexes.
Array 900miRNA microarray labeling kits are offered specifically for use with microRNA, siRNA and other small RNA molecules (tRNA, 5S rRNA, nuclease fragments, etc).
The Protein 280 ex lifetime spectrofluorometer measures three fluorescence lifetimes in just a few minutes. Time-Correlated Single-Photon Counting, a time-resolved fluorescence technique, is used to record reproducible lifetime data.
The ChIP 1000 Chemical Inkjet Printer (Shimadzu Biotech) is a new tool for proteomics analysis (peptide fingerprint mapping), protein macroarray analysis, and nano-Western analysis. Developed in partnership with Proteome Systems Ltd.
MabSelect Xtra is a recombinant protein A-based chromatography medium that captures antibodies with efficiency and economy. It is engineered to provide high dynamic binding capacity.
Avance II NMR (Bruker BioSpin Corp.) spectrometers incorporate second-generation (2G) digital receiver (DR) technology, which improves NMR detection fidelity.
Cell Lab Quanta compact flow cytometry system combines Coulter volume measurement with two-color fluorescence capabilities for accurate, multi-parameter cell counting and sizing.
Pronouncements of the “post genomic age” notwithstanding, genome sequencing is as relevant today as before the Human Genome Project began seventeen years and $2.7 billion ago. If the promise of genomics is ever to be realized, then clearly the most challenging sequencing work lies.