Fluorescence Recovery After Photobleaching (FRAP) is a non-invasive technique with numerous applications in cell biology. The technique enables the observation of dynamic movement of fluorescence-tagged molecules within living cells under light microscopes.
Reductive Amination Toolkit provides the resins required to optimize reaction conditions for amine synthesis and purification using reductive amination. This reaction is a powerful tool routinely used in generating structurally diverse drug candidates.
CodeLink UniSet Mouse 20K I Bioarray enables scientists tostudy gene expression across much of the mouse genome in a singleexperiment for drug target identification, pathway characterization, anddrug effect predictions.
By using immunoaffinity technology to specifically target and remove six high-abundance proteins from human blood serum, the Multiple Affinity Removal System facilitates the identification of more rare proteins that could serve as drug targets or biological markers.
The Web site http://www.mutationdiscovery.com has been updated with a new database reflecting genetic variations in the mouse. The site includes the genomic DNA sequences of almost 23,000 human genes and annotated information on variations that have been observed in these genes.
Monoclonal antibody offered to glutamate NMDA Receptor subunits 3A and 3B recognizes both NR3A and NR3B subunits in Western Blot and immunohistochemistry applications. NR3B is the final member of the NMDA subtype of the glutamate receptor (NMDAR) family to be cloned and characterized.
The Cultrex extra-cellular matrix product line has been expanded. Product additions include BME in PBS, BME staining kit, Cell Recovery Solution, Poly-L-Lysine, Rat Tail Collagen, and Bovine Collagen I. Cultrex products are used for cell differentiation, angiogenesis, and tumor cell invasion.
CellTiter-Blue cell viability assay provides a homogenous method for estimating the number of viable cells present in multiwell plates.
Low Level Bio Safety Enclosure protects the process being performed inside the enclosure with laminar flow HEPA filtered air, and protects the technician by maintaining a safety face velocity at the sash opening.
DENALI 120ÅA silica-based columns and media are used for the separation of enhanced small molecules.
Fraction-PREP systems provide formulations of buffers and reagents for preparation of highly enriched cellular fractions from mammalian cells. The simple procedure provides pure fractions.
Adiponectin (Acrp30), an adipocyte-specific secreted protein, circulates in plasma and plays a role in various physiological processes, such as energy homeostasis and obesity. Active recombinant human, mouse, and rat adiponectin was expressed using perspective adiponectin of cDNA.
RNAi targets gene silencing, and is achieved in mammalian cells through the use of short interfering RNA molecules, or siRNAs. RNAi has accelerated the functional characterization of disease-relevant genes for drug discovery and basic research efforts.
Global 2019 rodent diet is designed to improve reproduction and performance of genetically engineered mice and other poorly performing rodents. It contains 19% protein and 9% fat content, and meets the nutrient requirements of gestation, lactation, and early growth of rats and mice.
Custom monoclonal and polyclonal antibody development through genetic immunization involves direct immunization of the host animal with plasmid DNA encoding a protein of interest. The immunized host then produces the encoded protein and raises antibodies.