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ADME/Tox Databases

October 1, 2004 4:40 am | Articles | Comments

Thirteen databases have been introduced that contain measured ADME/Tox properties for a range of chemical compounds, covering seven endpoints including Blood Brain Barrier, Human Intestinal Absorption, log D, log P, Mutagenicity, Plasma-Protein Binding, and Water Solubility.

Informatics Platform

October 1, 2004 4:40 am | Articles | Comments

Nonlinear Dynamics Progenesis Discovery Informatics platform supports the gel-based component of the company's proteomic service offering. The product automates high-throughput gel analysis, data mining, and support of lab-based research.

Genomic/Proteomic Sequence Search

October 1, 2004 4:40 am | Articles | Comments

GenomeQuestLive! genomic/proteomic sequence search service enables both functional and

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Knowledge Modeling System

October 1, 2004 4:40 am | Articles | Comments

Genstruct's Molecular Epistemics platform enables the identification of mechanisms of action for small molecule drugs, mechanisms of drug resistance and potential biological markers to support decision making on clinical compounds.

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Finding the Lessons in VIOXX 9/30/04

September 30, 2004 12:48 pm | Articles | Comments

By Elizabeth Tolchin

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FRET And FRET-FLIM Microscopy Imaging Of Localized Protein Interactions In Living Cell Nucleus

September 30, 2004 9:44 am | Articles | Comments

FRET microscopy imaging is widely used to detect protein-protein interactions inside living cells. This application note describes the use of one and two-photon FRET and in characterizing the dimerization of C/EBP?

Attaching Substrates to DNA Bares Unknown Reactions 9/29/04

September 29, 2004 11:13 am | Articles | Comments

By Elizabeth Tolchin

One Pharma's Trash Is Another's Pharmacogenomic Treasure 9/28/04

September 28, 2004 8:11 am | Articles | Comments

By Elizabeth Tolchin

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Bulky Molecules Seek Out SNPs 9/27/04

September 27, 2004 9:18 am | Articles | Comments

By Elizabeth Tolchin

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Weekly News Roundup 9/24/04

September 24, 2004 11:39 am | Articles | Comments

By Elizabeth Tolchin

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Quantitative Diagnostics from Yale Forms Basis of New Company 9/23/04

September 23, 2004 10:20 am | Articles | Comments

By Elizabeth Tolchin

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Tube Shows Minimal Affinity For Peptides And Proteins

September 23, 2004 6:42 am | Articles | Comments

Sample preparation in biological and biotechnological systems plays an important role in the success of many processes. It is a requirement that the material of the micro test tubes used must possess low affinity for proteins and peptides to prevent adsorption of the sample material to the tube surface.

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Linear RNA Amplification For Expression Analysis

September 23, 2004 6:42 am | Articles | Comments

RNA amplification is rapidly becoming a routine and necessary step when preparing samples for expression analysis— particularly when using microarrays. RNA amplification provides the sensitivity to detect expression differences of low abundance transcripts that is critical to obtaining a complete understanding of the biology of a given system.

Shotgun Microarraying a Favorite for Disease Studies 9/22/04

September 22, 2004 12:02 pm | Articles | Comments

By Elizabeth Tolchin

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Algorithm Quickly Exposes Regulatory Elements 9/21/04

September 21, 2004 12:50 pm | Articles | Comments

By Elizabeth Tolchin

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