by Elizabeth Tolchin Two new products for small, interfering RNA (siRNA) targeting are promising reliable gene silencing for researchers in functional genomics or drug target identification, according to the companies who released the products.
Real-time PCR offers a quantitative method for viral and bacterial pathogen detection, measurement of gene expression, and mutation detection.
GenomePlex whole genome amplification (WGA) point of use kit (Rubicon Genomics, Inc.) complements Rubicon's WGA in-house service business that was launched earlier this year.
OriGene Technologies Inc. has announced the addition of the GPCR CloneSet, a designated subset of over 300 full-length human non-olfactory G protein-coupled receptors, to the TrueClone Collection product line.
Label IT®μ Array Biotin Kits (Mirus Corp.) offer a single color, chemical labeling method optimized for use in microarray applications.
Yeast shuttle vector pORF-CLONE provides cost-effective selection of clones containing long cDNA inserts with a correct open reading frame (ORF).
Ambion's pSilencer adeno 1.0-CMV System combines the advantages of adenoviral vectors with an efficient siRNA expression system. It allows easy delivery of an siRNA expressing construct into many difficult to transfect cells, including primary cells.
Immobiline DryStrip gels extend the pH range in the basic region from 10 to 11, compared to the traditional pH 3-10, yielding a broad overview of protein composition, enhancing gel resolution, and improving reproducibility of the protein pattern in the extreme basic region.
BD Qtaq DNA Polymerase Mix is a full-length Taq DNA polymerase optimized for use with BD Qzyme Assays and most other qPCR detection applications and provides increased DNA and RNA quantitation sensitivity and reproducibility in qPCR and RT-PCR.
Supercoiled DNA Marker Set is suitable for size analysis of cDNA clones and BAC subclones by agarose minigel or Pulse-Field Gel Electrophoresis (e.g., FIGE, CHEF). It can also be used for the size analysis of any supercoiled plasmid larger than 8 kb and other extra-chromosomal DNAs from any source.
Solution phase isoelectric focusing with the ZOOM IEF Fractionator provides reproducible
by Elizabeth Tolchin A picture of the inner structure of RNA polymerase is providing a better picture of the transcription process. The structure, transcription factor IIB (TFIIB) bound to RNA polymerase II (pol II), was solved by a group at Stanford University, Stanford Calif.
by Elizabeth Tolchin MicroRNAs are frequently located in cancer-associated regions of the genome and can act as both tumor suppressor genes and oncogenes, according to a new study. The association could lead to the use of microRNAs in cancer treatment.
by Elizabeth Tolchin An assay technology for screening and select compounds that regulate immune responses developed by the University of British Columbia, Vancouver, Canada, was licensed recently to the Canadian company GeneMax Pharmaceuticals Inc., also in Vancouver.
by Elizabeth Tolchin Catalyst Biosciences Inc., San Francisco, a biotechnology start-up company focusing on the engineering of recombinant proteases as therapeutics in the areas of cancer and inflammation, recently licensed a method for rapidly determining the substrate specificity of a protease from the University of California, San Francisco (UCSF).