Researchers Identify Gene for Age-Related Blindness
Linking methylation to DNA damage
Preclinical oncology compound from J&JPRD
A range of sterilization-resistant laboratory labels are available for wet, dry and radiation sterilization processes.
Cardiac related antibody and antigen line offers numerous monoclonals specific to the human cardiac isoform of Troponin I (cTnI). These antibodies have been characterized by Western blot for reactivity with Troponin I from different animal species.
Three M.O.M. (Mouse-on-Mouse) kits are offered for the localization of mouse primary antibodies on mouse tissue sections. The kits allow mouse primary antibodies to be stained while avoiding interfering background due to the detection reagents binding endogenous mouse antibody.
Signaling research line includes antibodies for the Akt pathway, cell cycle and Checkpoint control, cytokines, DNA damage, the NfkB pathway and for ubiquitin.
Expanded line of iso-IHC Core kits come with the components required for performing iso-IHC, except the substrate-chromogen system, which the user can select from the Core Kit Accessories. Users have the freedom to work with the chromogenic system of choice.
Caspase-Glo 8 and Caspase-Glo 9 assays offer sensitive apoptosis detection. The homogeneous assay protocol for Caspase 8 & 9 provides results in 20 minutes.
Purified monoclonal antibody raised against human Interleukin-19 is available from R&D Systems. IL-19 is a novel member of the multifunctional IL-10 family. It is secreted as a monomer that contains a unique bundle of seven amphipathic helices.
Lightspeed kinase assays, quenching fluorescence-based assays for drug discovery, are offered for PKCa (diabetes and leukemia), Akt-1 (cancer), Src (cancer) and p38a (leukemia and lymphoma).
Anti-mPDCA-1 antibodies provide specific detection and isolation of murine plasmacytoid dendritic cells (mPDCs).
Human IL-2 and Bovine TNF alpha Screening Sets are offered for development of 5 colorimetric ELISA plates each.
Cell Cycle Assay (Guava Technologies, Inc.) incorporates staining reagents pre-combined in a single optimized format, eliminating reagent preparation following cell fixation. Protocols are offered for use with either individual tubes or 96-well microplates, minimizing assay development time.
In vitro-derived, recombinant antibody is targeted against human Cyclophilin A, which is indicated to play an important role in the mechanism of protein folding. Recently a number of diseases have been linked to protein folding problems.