Non-antibody cartilage oligomeric matrix protein (COMP) fused to CD40 blocks CD40L-meditated proliferation of B-cells. Shown to display affinity for its ligand, CD40:COMP does not require any crosslinking reagent to effectively bind CD40L (CD154).
by Don Monroe, PhD Beyond Genomics Inc., Waltham, Mass., concluded separate drug discovery and development agreements with two major pharmaceutical firms within the last several weeks.
Small interfering RNAs (siRNAs) are a powerful tool for RNA interference (RNAi) experiments used to down regulate specific gene expression, with hundreds of papers now published each month.
Cobalt-based Protein Purification Resin Does Not Bind E. coli SlyD, A Common Contaminant in Ni-NTA IMACFebruary 9, 2004 7:21 am | Articles | Comments
E. coli SlyD, a prolyl isomerase, specifically binds divalent metal ions, which can result in significant contamination of IMAC preparations of heterologously expressed His-tagged proteins.
Compact refrigerated centrifuge 5702 R has a maximum speed of 3000 × g and offers a choice of fixed-angle or swing-bucket rotor. Round bottom and conical tubes from 1.1 ml to 85 ml can be centrifuged, as can 20 × 10 ml blood tubes, or 30 × 15 ml conical tubes.
Watson-Marlow Bredel 500 Series peristaltic pumps provide sterility and zero contamination. PumpSil Platinum Cured Silicone tubing further enhances the fermentation process and offers improved batch consistency.
UV PCR Workstation brings together UV light and antimicrobial stainless steel to create a protective environment against PCR contamination. The unit's chamber can be decontaminated between procedures with high intensity shortwave 254 nm UV.
SANYO Biomedical has introduced comprehensive upgrades in laboratory equipment door, lid and
The HVS448 High Voltage Sequencer provides precise control of MEMS and microfluidics experiments. The HVS448 provides eight channels that can each function as high voltage supplies and precision current and voltage sensors.
Millipore has announced a complete line of consumables and accessories for its Milli-Q water purification systems. Plug-in Q-Gard® purification packs are tailored to particular feed water sources.
Nor-Lake has released a new line of BOD refrigerators and stability cabinets. These cabinets offer an operating range of 4 C to 70 C and are available in 21, 30, 48 and 76 cu/ft models.
PRO homogenizers are available hand-held or post-mounted with the ability to homogenize various volumes from 0.03 ml to over 40 liters at top speeds of 30,000 rpm.
Ultra-Centrifugal Mill ZM features a Powerdrive unit that ensures high performance with increased torque. Even with temporary overloads, powerful throughput is provided.
Harris® Cryostar® cryogenic storage freezers operate at temperatures of 𤩼 C and 𤪆 C. Chest models in the Harris Cryostar range employ a single compressor refrigeration system that avoids the expense and hazard of liquid nitrogen.
The Kebby Power Crimp offers quick, precise crimping/sealing of caps/tops to vials and bottles. It can be used in the stand or removed in a matter of seconds for hand operated use. Compatible with over 100 industry standard sizes and types of heads from 7.5 mm to 43 mm.